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Antibodies for Zika and Dengue Viruses
Applications
ELISA
Western Blot
Immunohistochemistry
Specificity
Human monoclonal
Technical Summary
Zika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion....
Published: 7/30/2024
Contributor(s): Jens Wrammert, Mark Mulligan
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Glycoprotein Tetramer for Identifying Antigen-specific B Cells
Application
Ectodomain of viral glycoprotein tetramers detects antigen-specific memory B Cells.
Key Benefits
Viral glycoprotein tetramers detect antigen-specific memory B cells in the peripheral blood and tissues.
Hepatitis C virus E2 protein triggers immune response, which may yield an effective vaccine against hepatitis C virus.
Market Summary
Hepatitis...
Published: 10/28/2024
Contributor(s): Arash Grakoui, Joseph Marcotrigiano
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Sodium-Hydrogen Antiporter 3 (NHE3) Antibody
Applications
Western Blot
Immunoprecipitation
Specificity
Human
Subtype
Rabbit Polyclonal
Technical Summary
Sodium-hydrogen antiporter 3 (NHE3) is found in the nephron of the kidney and in the apical membrane of enterocytes of the intestine. Intestinal epithelial cells express multiple forms of NHEs among which, type 3 is the primary brush-border...
Published: 9/26/2024
Contributor(s): Chang-Hyon Chris Yun
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Antibody that Binds to Lysophosphatidic Acid Receptor 5 (LPAR5)
Applications
Western Blot
Immunoprecipitation
Specificity
Human
Subtype
Rabbit Polyclonal
Technical Summary
Lysophosphatidic acid (LPA) is a small, bioactive glycerophospholipid that acts as an extracellular signaling molecule in most eukaryotic tissues. Research suggests that LPA may play a role in pathological conditions such as inflammation,...
Published: 9/26/2024
Contributor(s): Chang-Hyon Chris Yun
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Antibody That Reacts with Inositol Triphosphate (IP3) Receptor-binding Protein (IRBIT)
Applications
Western Blot
Immunoprecipitation
Specificity
Human
Subtype
Rabbit Polyclonal
Technical Summary
Calcium is responsible for regulating various cellular processes. The elevation of intracellular calcium regulates the activity of Na+/H+ exchanger 3 (NHE3). Emory inventors have identified a polyclonal antibody which cross reacts...
Published: 9/26/2024
Contributor(s): Chang-Hyon Chris Yun
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Serotonin Transporter (SERT) Monoclonal Antibody
Applications
Immunohistochemistry
Specificity
Rat serotonin transporter - N-terminus
Subtype
Monoclonal Mouse IgG1
Technical Summary
The serotonin transporter (SERT) is a monoamine transporter protein, which works to recycle serotonin (5-HT) from the synaptic cleft thus regulating the 5-HT concentration in the synapse. SERT is the site of action...
Published: 9/26/2024
Contributor(s): Kenneth Gould, Jeremy Dahl
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mMob3/Phocein (clone 16E2) Polyclonal Antibody
Application
Western Blot
Specificity
Human, Mouse, Rat
Subtype
Rabbit Polyclonal
Immunogen
KLH-Linked Peptide
Technical Summary
mMob3 also called Phocein (and was called mMob1 - see publication below) is a mammalian class II homolog of yeast MOB1 that appears to be a substrate for PP2A. In S. cerevisiae, MOB1 is an essential gene that is required...
Published: 12/4/2024
Contributor(s): David Pallas
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ß-secretase (BACE) Monoclonal Antibody
Applications
Immunohistochemistry
Western Blot
Immunprecipitation
Specificity
β -secretase (BACE) of mouse, rat, and human origin.
Subtype
Mouse Monoclonal
Technical Summary
β -secretase (BACE) is an aspartic-acid protease important to the formation of the amyloid-β peptides that form senile plaques in brains of Alzheimer's...
Published: 9/26/2024
Contributor(s): Allan Levey
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Presenillin 1 N-Terminal Monoclonal Antibody
Applications
Immunoblotting
Immunocytochemistry
Specificity
Human Presenilin-1 N-terminal
Subtypes
Rat monoclonal
Technical Summary
By immunoblotting applications the antibody recognizes a predominant 32 kDa polypeptide in a varitety of samples including PC12 cells transfected with human PS1, complimentary DNA brain biopsy specimens from...
Published: 9/26/2024
Contributor(s): Allan Levey
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Presenillin 1 C-Terminal Monoclonal Antibody
Applications
Immunoblotting
Immunohistochemistry
Specificity
Human Presenilin-1 C-terminal
Subtypes
Mouse Monoclonal
Technical Summary
By immunoblotting applications the antibody recognizes a predominant 32 kDa polypeptide in a varitety of samples including PC12 cells transfected with human PS1, complimentary DNA brain biopsy specimens from...
Published: 9/26/2024
Contributor(s): Allan Levey
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