|
Frog Skin Peptides for Treatment of Human Influenza Viruses
Application
A therapeutic peptide that treats Influenza A virus
Key Benefits
New method of action compared to antiviral drugs currently in use.
Therapeutic peptide is virucidal against drug resistant strains.
Market Summary
Worldwide seasonal influenza epidemics can impact 5 – 15% of the population. The occurrence of vaccine mismatch...
Published: 7/30/2024
Contributor(s): Joshy Jacob, David Holthausen, Song Lee, Sanil George
|
|
ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 10/28/2024
Contributor(s): Erwin Van Meir
|
|
Antibodies for Zika and Dengue Viruses
Applications
ELISA
Western Blot
Immunohistochemistry
Specificity
Human monoclonal
Technical Summary
Zika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion....
Published: 7/30/2024
Contributor(s): Jens Wrammert, Mark Mulligan
|
|
Respiratory Syncytial Virus Strain A2-2-20F
Application
Strain of respiratory syncytial virus (RSV) for vaccine and therapeutic research and development.
Key Benefits
Higher early viral load.
Induces greater necrotic airway damage and neurophil infiltration.
Market Summary
RSV is a highly contagious and ubiquitous virus that causes respiratory tract infections in individuals of all ages,...
Published: 9/26/2024
Contributor(s): Martin Moore
|
|
TaqMan Array Cards for Pneumococcal Detection and Serotyping
ApplicationDiagnostic for identifying Streptococcus pneumonia serotypes.Key BenefitsAllows for rapid detection and serotype identification of Streptococcus pneumonia infections.Market SummaryStreptococcus pneumonia (Spn) is a gram-positive bacteria and significant human pathogen responsible for most pneumonia cases. Typically, Spn resides asymptomatically...
Published: 7/30/2024
Contributor(s): Jorge Vidal Graniel, Fuminori Sakai, Lesley McGee, Velusamy Srinivasan
|
|
Repurposed Kinase Inhibitor for Treatment of Multidrug Resistant Tuberculosis
ApplicationProtein tyrosine kinase inhibitor (imatinib) used as a treatment to prevent multiple drug-resistant tuberculosis lethality and latent reactivation.Key BenefitsEffective against drug resistant strains of tuberculosis.May be used in combination with current first-line treatments of TB.Market SummaryTuberculosis (TB) is a chronic infectious...
Published: 10/28/2024
Contributor(s): Daniel Kalman
|
|
Respiratory Syncytial Virus (RSV) A2 Expressing Firefly Luciferase
Application
Recombinant RSV strain expressing firefly luciferase and the F & G genes from clinical strain A2001/2-20 for research and development of vaccines.
Key Benefits
F & G proteins included in this strain show different behavior than those of the typical A2 strain proteins.
May be adapted in a variety of assays, enabling the identification...
Published: 9/26/2024
Contributor(s): Martin Moore, Christopher Stobart
|
|
Plasmid for Respiratory Syncytial Virus (RSV) Vaccine Development & Research
Applications
Bacterial artificial chromosome (BAC) plasmid containing the antigenomic sequence A2-BAG-BAF derived from multiple strains of RSV.
Key Benefits
Viral DNA is contained in a BAC, allowing for efficient mutagenesis and recombineering of viral DNA.
BAC is stable and can be used for cloning in common bacteria types like E. coli.
Provides...
Published: 9/26/2024
Contributor(s): Martin Moore, Anne Hotard (Lopez-Ona)
|
|
Recombinant Respiratory Syncytial Virus (RSV) Firefly Luciferase Reporter Strain
Application
Modified recombinant syncytial virus (RSV) strain expressing a bioluminescent reporter protein for high throughput screening and vaccine development.
Key Benefits
Provides a new high throughput screening tool for RSV vaccine development and drug discovery.
Firefly luciferase based assays show better signal-to-noise than fluorescence-based...
Published: 9/26/2024
Contributor(s): Richard Plemper, Martin Moore
|
|
Recombinant RSV Strains Expressing Renilla Luciferase and G & F Proteins
Application
Recombinant respiratory syncytial virus (RSV) strains expressing the G and F Proteins from RSV strains as well as renilla luciferase for use in drug and vaccine screening.
Key Benefits
Provides new and needed tool for screening potential RSV therapies, ensuring they are broadly effective against multiple, distinct strains of the virus....
Published: 9/26/2024
Contributor(s): Martin Moore, Jia Meng
|
