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Frog Skin Peptides for Treatment of Human Influenza Viruses
Application
A therapeutic peptide that treats Influenza A virus
Key Benefits
New method of action compared to antiviral drugs currently in use.
Therapeutic peptide is virucidal against drug resistant strains.
Market Summary
Worldwide seasonal influenza epidemics can impact 5 – 15% of the population. The occurrence of vaccine mismatch...
Published: 7/30/2024
Contributor(s): Joshy Jacob, David Holthausen, Song Lee, Sanil George
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Frog Skin Peptides for Treatment of Zika Viruses
Application
A therapeutic peptide that treats Zika Virus.
Key Benefits
Potential therapeutic to fight against the growing threat of the Zika virus.
Peptide is fast acting and destroys Zika virions within 5 minutes of exposure.
Market Summary
Zika is an infectious disease spread primarily by Aedes mosquitoes and results in symptoms similar to...
Published: 11/20/2024
Contributor(s): Joshy Jacob, Song Lee, David Holthausen, Sanil George
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Infection Control System for Resuscitation and Airway Management
Application
Collapsible, single-use ‘pop-up tent’ system to prevent transmission of infectious disease during resuscitation and airway management.
Key Benefits
Provides protective barrier to prevent transmission of infectious disease.
Allows adequate access to the patient for airway management procedures.
Single-use to minimize infection...
Published: 7/30/2024
Contributor(s): Adam Klein, Russell Gore, David Wright
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ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 10/28/2024
Contributor(s): Erwin Van Meir
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Antibodies for Zika and Dengue Viruses
Applications
ELISA
Western Blot
Immunohistochemistry
Specificity
Human monoclonal
Technical Summary
Zika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion....
Published: 7/30/2024
Contributor(s): Jens Wrammert, Mark Mulligan
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Respiratory Syncytial Virus Strain A2-2-20F
Application
Strain of respiratory syncytial virus (RSV) for vaccine and therapeutic research and development.
Key Benefits
Higher early viral load.
Induces greater necrotic airway damage and neurophil infiltration.
Market Summary
RSV is a highly contagious and ubiquitous virus that causes respiratory tract infections in individuals of all ages,...
Published: 9/26/2024
Contributor(s): Martin Moore
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TaqMan Array Cards for Pneumococcal Detection and Serotyping
ApplicationDiagnostic for identifying Streptococcus pneumonia serotypes.Key BenefitsAllows for rapid detection and serotype identification of Streptococcus pneumonia infections.Market SummaryStreptococcus pneumonia (Spn) is a gram-positive bacteria and significant human pathogen responsible for most pneumonia cases. Typically, Spn resides asymptomatically...
Published: 7/30/2024
Contributor(s): Jorge Vidal Graniel, Fuminori Sakai, Lesley McGee, Velusamy Srinivasan
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Transgenic Mice for Studying Cell-Type Specific Immunity
ApplicationTransgenic mice expressing floxed mitochondrial antiviral-signaling protein (MAVS) for study of cell-type and tissue-specific immunity.Key BenefitsStudy cell-type and tissue-specific immunity.Can be crossed using CRE-recombinase system.Technical SummaryMitochondrial antiviral-signaling protein (MAVS) is a protein in humans that is encoded...
Published: 11/20/2024
Contributor(s): Mehul Suthar
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Repurposed Kinase Inhibitor for Treatment of Multidrug Resistant Tuberculosis
ApplicationProtein tyrosine kinase inhibitor (imatinib) used as a treatment to prevent multiple drug-resistant tuberculosis lethality and latent reactivation.Key BenefitsEffective against drug resistant strains of tuberculosis.May be used in combination with current first-line treatments of TB.Market SummaryTuberculosis (TB) is a chronic infectious...
Published: 10/28/2024
Contributor(s): Daniel Kalman
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CXCR4 Antagonists for the Treatment of Cancer
Application
Small molecules containing either the piperidine or piperazine core which act as antagonists to C-X-C chemokine receptor type 4 (CXCR4) and may be orally administered.
Key Benefits
Orally administered CXCR4 antagonists with diverse clinical applications in oncology.
Mobilize white blood cells in mice in a dose-dependent manner.
Cause...
Published: 11/20/2024
Contributor(s): Lawrence (larry) Wilson, Dennis Liotta, John Wiseman, Michael Natchus
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