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Anticancer Agent with N-Glycan Specificity
Application
An engineered protein for targeting disease-associated N-glycans.
Key Benefits
High affinity, pH insensitive, no cofactors required.
Applications in anticancer and antiviral therapeutics and research.
Can aid in manufacturing monoclonal antibodies with desired N-glycosylation properties.
Market Summary
Glycosylation involves post-translation...
Published: 1/20/2026
Contributor(s): Eric J. Sundberg, Diego Sastre, Maros Huliciak
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Combinatorial Therapy for Preserving Muscle Mass During Weight Loss
Application
A combinatorial therapy to preserve muscle mass during semaglutide weight loss treatment.
Key Benefits
Preserves lean mass during semaglutide treatment in preclinical mouse models.
Increases overall fat loss without affecting food/water intake during semaglutide treatment in preclinical mouse models.
Market Summary
The prevalence...
Published: 2/23/2026
Contributor(s): Todd Golde, Yong Ran, Eric Krause, Annette De Kloet, Karen Scott
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Anti-Green Fluorescent Protein Antibodies
Applications
Western Blot
Immunocytochemistry
Immunohistochemistry
Specificity
Vertebrates
Subtype
Chicken Polyclonal
Immunogen
His-tagged green fluorescent protein of the bioluminescent hydrozoan jellyfish (Aequorea Victoria).
Technical Summary
Drs. Tomasiewicz, Wood, & Flaherty have created a polyclonal anti- green fluorescent...
Published: 1/28/2026
Contributor(s): Henry Tomasiewicz, John Wood, Denise Flaherty
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EF-Tu Targeting Antibody for Infection Treatment
Application
Therapeutic monoclonal antibodies directed to Elongation Factor-Tu (EF-Tu) for the treatment of infections.
Key Benefits
An antibody that targets the protein EF-Tu, which is present on many types of bacteria involved in life-threatening infections.
A research-grade antibody has been developed with animal data showing the ability to...
Published: 9/22/2025
Contributor(s): Joanna Goldberg, Dina Moustafa
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BG505 SOSIP Vaccine Elicited Neutralizing Monoclonal Antibodies for HIV
Application
ELISA
Western Blot
Immunohistochemistry
Specficity
HIV-1 BG505 Env protein (clone name: YRK01, YRK02).
Subtype
Monoclonal antibody.
Immunogen
HIV-1 BG505 SOSIP Env trimer.
Technical Summary
HIV-1 envelope glycoprotein (Env) is a membrane protein complex involved in receptor recognition and viral fusion with CD4+ T cells...
Published: 1/20/2026
Contributor(s): Cynthia Derdeyn, Tysheena Charles
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Galectin-9 Directed CAR T-cells for Overcoming Resistance to Chemotherapy in Hematological Malignancies
Application
Anti-human Galectin-9-directed chimeric antigen receptor (CAR) T-cells for treatment of hematological malignancies (B-ALL, T-ALL, and DLBCL) in normal, overweight, and obese patients.
Key Benefits
Can be used as a stand-alone or in-combination product to treat patients with hematological malignancies, particularly overweight and obese...
Published: 2/5/2026
Contributor(s): Curtis Henry, Miyoung (Mi-Young) Lee, Sunil Raikar, Jamie Hamilton, Anthony Ross
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Trimeric Immunogen for HIV-1 Vaccination
Application
Trimeric gp120 immunogen that induces broadly cross-reactive V1V2-antibodies for HIV-1 vaccine.
Key Benefits
Possible oral administration.
Broadly cross-reactive against HIV-1 panel.
Promotes antibody responses as both a primary immunogen and boosting immunogen.
Market Summary
Antiretroviral therapy (ART) has dramatically prolonged...
Published: 7/22/2025
Contributor(s): Rama Rao Amara, Andrew Jones, Raghavan Varadarajan, Sannula Kesavardhana
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Antibody Therapy for Varicella Zoster Virus
Application
Human monoclonal antibodies for the treatment of varicella zoster virus (VZV).
Key Benefits
Human monoclonal antibodies can limit the spread of VZV.
gH-specific antibodies are complement-independent.
Market Summary
Varicella Zoster Virus (VZV) causes varicella, more commonly known as chickenpox. Once the illness resolves, the virus...
Published: 1/20/2026
Contributor(s): Rafi Ahmed, Nicole Sullivan
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Glycoprotein Tetramer for Identifying Antigen-specific B Cells
Application
Ectodomain of viral glycoprotein tetramers detects antigen-specific memory B Cells.
Key Benefits
Viral glycoprotein tetramers detect antigen-specific memory B cells in the peripheral blood and tissues.
Hepatitis C virus E2 protein triggers immune response, which may yield an effective vaccine against hepatitis C virus.
Market Summary
Hepatitis...
Published: 1/20/2026
Contributor(s): Arash Grakoui, Joseph Marcotrigiano
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Promising Antibodies Target Virus Glycoprotein for Vaccination and Therapy
ApplicationAntibodies that bind and neutralize Ebola virus glycoprotein (GP) for use in vaccination or treatment of Ebola virus disease.Key BenefitsHigher binding affinity for Ebola virus GP than closest competitor.Can be used prophylactically or for treatment of Ebola virus disease.Market SummaryThe Ebola virus is an RNA virus with a membrane composed...
Published: 9/3/2025
Contributor(s): Rafi Ahmed, Carl Davis, Erica Ollmann Saphire
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