Protein Phosphatase 2A Regulatory A Subunit (4G7) Monoclonal and (R39) Polyclonal Antibodies
Applications
- Immunoblotting
- Immunofluorescence
- Histochemistry
Specificity
Monoclonal and polyclonal antibodies that recognize the PP2A A subunit
Subtype
Anti-mouse
Technical Summary
The inventor has made monoclonal (4G7) and polyclonal (R39) antibodies to the PP2A A subunit peptide (DP32). Most A subunit antibodies available are polyclonal antibodies. This hybridoma provides a continuous source of monoclonal antibody that will help provide consistency of results better than with polyclonal antibodies. May be useful for detecting A alpha or A beta mutants or expression changes that may contribute to cancer or Alzheimer's Disease risk. Mutations in the A subunit may also be able to be detected in cancer in part through using this antibody.
Publications
Journal of Biological Chemistry. 278: 42, 40829-40836 (2003).
Journal of Biological Chemistry. 274: 20, 14382-14391 (1999).
Patent Information
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