Technology Listings


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Dual Mobility Femur Prosthetic to Reduce Post-Operative Hip Dislocation
Application A new design of a modular hip implant with a rotational proximal junction in the femoral stem to minimize post-operative hip dislocation. Benefits Rotating femoral component alleviates torsional strain on implant, a primary cause of implant impingement and failure. Market Summary Peri-prosthetic hip dislocation is the number one...
Published: 8/17/2021       Contributor(s): George Guild, III
Predicting Treatment Response in Patients with Spinal Muscular Atrophy (SMA)
Application Prognostic model predicts treatment response to nusinersen (Spinraza®) in patients with spinal muscular atrophy. Key Benefits A prediction model using baseline CHOP-INTEND, IL-8, fractalkine, and MCP-1 accurately predicts CHOP-INTEND outcomes in children treated with nusinersen The model can also be incorporated into future therapeutic...
Published: 7/13/2021       Contributor(s): William Hu, Sumit Verma
Three-piece Partially Biodegradable Screw for Use in Ankle Surgery
Application Three-piece, partially biodegradable cannulated screw for use in syndesmosis ankle surgery. Key Benefits Implant removal is not necessary. Allows for both rigid initial fixation to allow syndesmotic healing and physiologic micro motion at the syndesmosis for long term support and function. Higher biomechanical strength than absorbable...
Published: 12/8/2020       Contributor(s): Jason Bariteau, Marissa McLaren, John Watson, Tyler Jenkins, Matthew (Matt) Metzger, Yuen Bak Ching
Myosoft: Automated Muscle Histology Analysis
Application Software to automatically measure muscle fiber types and sizes. Key Benefits Accurately identify and characterize different muscle fiber types within a sample. Market Summary Despite generations of technological advancements in disease interpretation and testing technologies, accurate diagnosis of myopathy remains a challenge. Myopathy,...
Published: 11/2/2020       Contributor(s): Hyojung Choo, H. Criss Hartzell, Jr., Lucas Encarnacion-Rivera, Steven Foltz
Small Molecules to Promote Bone Growth
Application Small molecule sclerostin-inhibitors to enhance the canonical Wnt pathways and promote BMP-induced osteoblast differentiation. Key Benefits Repurposing opportunities of FDA approved drugs. Lower cost compared to currently available monoclonal antibody or recombinant protein therapies. Stable compounds with established safety profiles...
Published: 12/3/2019       Contributor(s): Scott Boden, Steven Presciutti, Sreedhara Sangadala
Autoencoding Neural Networks with Applications to Brain-machine Interfaces
Application Machine learning software for brain-machine interface and neuro-stimulation device-controlling. Key Benefits Significantly improves machine learning performance by minimizing overfitting. Market Summary In machine learning (ML), autoencoder, a type of unsupervised artificial neural network, attempts to learn efficient data coding....
Published: 11/22/2019       Contributor(s): Chethan Pandarinath, Mohammadreza Keshtkaran
TGFβR3-based Biomaterial to Treat Bone Damage
Application PEG-MAL (Poly(ethylene glycol) methyl ether maleimide) polymer gel composition containing soluble TGFβ3R or embedded with modified TGFβ3R over-expressing cells for bone growth and repair therapy. Key Benefits Targets a non-BMP2 signaling pathway to improve BMP signaling. •Avoids complications associated with BMP2. Market...
Published: 9/20/2019       Contributor(s): Steven Goudy
ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 7/9/2019       Contributor(s): Erwin Van Meir
ADGRB1/BAI1 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B1, brain-specific angiogenesis inhibitor-1 (ADGRB1/BAI1) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB1/BAI1 gene. These mice were developed through homologous recombination and have LacZ gene knock-in. Mice were...
Published: 7/9/2019       Contributor(s): Erwin Van Meir
Surgical Device for Eyelid Ptosis Correction
ApplicationSurgical device to perform clamping, incision, and closure for correcting eyelid ptosis.Key BenefitsSimplifies the Müller muscle resection that decreases surgical procedure time.Eliminates the risk of cutting sutures that cause dehiscence and improves the final appearance.Market SummaryPtosis (drooping upper eyelids) is a common condition...
Published: 6/18/2019       Contributor(s): Denise Kim, Jacquelyn Borinski, Andrew Kolpitcke, Mohamad Ali Naja, Drew Padilla
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