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Dual Mobility Femur Prosthetic to Reduce Post-Operative Hip Dislocation
Application
A new design of a modular hip implant with a rotational proximal junction in the femoral stem to minimize post-operative hip dislocation.
Benefits
Rotating femoral component alleviates torsional strain on implant, a primary cause of implant impingement and failure.
Market Summary
Peri-prosthetic hip dislocation is the number one...
Published: 9/26/2023
Contributor(s): George Guild, III
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Predicting Treatment Response in Patients with Spinal Muscular Atrophy (SMA)
Application
Prognostic model predicts treatment response to nusinersen (Spinraza®) in patients with spinal muscular atrophy.
Key Benefits
A prediction model using baseline CHOP-INTEND, IL-8, fractalkine, and MCP-1 accurately predicts CHOP-INTEND outcomes in children treated with nusinersen
The model can also be incorporated into future therapeutic...
Published: 7/28/2023
Contributor(s): William Hu, Sumit Verma
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Three-piece Partially Biodegradable Screw for Use in Ankle Surgery
Application
Three-piece, partially biodegradable cannulated screw for use in syndesmosis ankle surgery.
Key Benefits
Implant removal is not necessary.
Allows for both rigid initial fixation to allow syndesmotic healing and physiologic micro motion at the syndesmosis for long term support and function.
Higher biomechanical strength than absorbable...
Published: 8/30/2023
Contributor(s): Jason Bariteau, Marissa McLaren, John Watson, Tyler Jenkins, Matthew (Matt) Metzger, Yuen Bak Ching
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Myosoft: Automated Muscle Histology Analysis
Application
Software to automatically measure muscle fiber types and sizes.
Key Benefits
Accurately identify and characterize different muscle fiber types within a sample.
Market Summary
Despite generations of technological advancements in disease interpretation and testing technologies, accurate diagnosis of myopathy remains a challenge. Myopathy,...
Published: 7/28/2023
Contributor(s): Hyojung Choo, H. Criss Hartzell, Jr., Lucas Encarnacion-Rivera, Steven Foltz
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Small Molecules to Promote Bone Growth
Application
Small molecule sclerostin-inhibitors to enhance the canonical Wnt pathways and promote BMP-induced osteoblast differentiation.
Key Benefits
Repurposing opportunities of FDA approved drugs.
Lower cost compared to currently available monoclonal antibody or recombinant protein therapies.
Stable compounds with established safety profiles...
Published: 9/15/2023
Contributor(s): Scott Boden, Steven Presciutti, Sreedhara Sangadala
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Autoencoding Neural Networks with Applications to Brain-machine Interfaces
Application
Machine learning software for brain-machine interface and neuro-stimulation device-controlling.
Key Benefits
Significantly improves machine learning performance by minimizing overfitting.
Market Summary
In machine learning (ML), autoencoder, a type of unsupervised artificial neural network, attempts to learn efficient data coding....
Published: 7/28/2023
Contributor(s): Chethan Pandarinath, Mohammad Reza Keshtkaran
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TGFβR3-based Biomaterial to Treat Bone Damage
Application
PEG-MAL (Poly(ethylene glycol) methyl ether maleimide) polymer gel composition containing soluble TGFβ3R or embedded with modified TGFβ3R over-expressing cells for bone growth and repair therapy.
Key Benefits
Targets a non-BMP2 signaling pathway to improve BMP signaling.
Avoids complications associated with BMP2.
Market...
Published: 7/28/2023
Contributor(s): Steven Goudy
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ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 7/28/2023
Contributor(s): Erwin Van Meir
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Surgical Device for Eyelid Ptosis Correction
ApplicationSurgical device to perform clamping, incision, and closure for correcting eyelid ptosis.Key BenefitsSimplifies the Müller muscle resection that decreases surgical procedure time.Eliminates the risk of cutting sutures that cause dehiscence and improves the final appearance.Market SummaryPtosis (drooping upper eyelids) is a common condition...
Published: 7/28/2023
Contributor(s): Denise Kim, Jacquelyn Borinski, Andrew Kolpitcke, Mohamad Ali Naja, Drew Padilla
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Femoroplasty Device that Repairs the Hip Bone
Application
Less invasive surgical alternative to a total hip replacement (THR) that restores the shape and function of the hip joint.
Key Benefits
Requires less invasive surgery of the hip, reducing recovery time.
Prevents the patient from needing a THR or delays it for at least 10 years.
Less expensive than a THR.
Market Summary
The femoral...
Published: 9/15/2023
Contributor(s): Zachary Bercu, Janice Newsome, Jonathan Martin, Elizabeth Marr, Nicholas Arce, Kathryn Martin
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