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tPAINT to Measure Molecular Forces in Live Cells
Application
DNA-based probes to measure the nanoscale distribution of piconewton molecular forces in live cells.
Key Benefits
Provides maps of integrin tension with up to ˜25 nm resolution and piconewton force sensitivity for live-cell imaging.
The tPAINT can be performed on a commercial TIRF microscope.
Market Summary
Emory inventors...
Published: 11/17/2020
Contributor(s): Joshua Brockman, Hanquan Su, Khalid Salaita
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Myosoft: Automated Muscle Histology Analysis
Application
Software to automatically measure muscle fiber types and sizes.
Key Benefits
Accurately identify and characterize different muscle fiber types within a sample.
Market Summary
Despite generations of technological advancements in disease interpretation and testing technologies, accurate diagnosis of myopathy remains a challenge. Myopathy,...
Published: 11/2/2020
Contributor(s): Hyojung Choo, H. Criss Hartzell, Jr., Lucas Encarnacion-Rivera, Steven Foltz
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Automated Multiple Needle Detection For Brachytherapy
Application
Workflow to detect multiple needles in three-dimensional ultrasound images.
Key Benefits
Does not require specialized ultrasound pulses or hardware.
Detects multiple needles with low error.
Market Summary
Many minimally invasive procedures require inserting a needle to access a target site inside the patient body, avoiding the requirement...
Published: 11/2/2020
Contributor(s): Xiaofeng Yang, Tian Liu, Yupei Zhang, Pretesh Patel
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Amino Acid-Derived Radiotracer Compounds for PET Cancer Imaging
Application
New class of fluorine-18 labeled amino acid-derived radiotracer compounds for positron emission tomography (PET) cancer imaging.
Key Benefits
Next generation of cancer imaging agents.
Enhanced sensitivity to detect glioblastoma, prostate cancer and other cancers.
Market Summary
PET imaging is a type of nuclear medicine procedure...
Published: 11/2/2020
Contributor(s): Mark Goodman, Lanny Liebeskind, Thomas Pickel
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Targeted Theranostic NanoToxin for Treating Metastatic and Drug-resistant Tumors
Application
Magnetic theranostic nano-toxin for imaging and drug delivery applications in cancer therapy.
Key Benefits
Induces tumor cell death via a different biological mechanism, compared to current chemotherapeutics, to overcome drug resistance mechanisms in tumor cells.
Delivers high levels of therapeutic agents into metastatic tumors, while...
Published: 11/2/2020
Contributor(s): Lily Yang, Xiangxue Guo, Hui Mao, Wei Chen
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Attenuation Correction in Quantitative PET Imaging
Application
Software to perform attenuation correction in quantitative PET imaging.
Key Benefits
Improves quantification accuracy and reliability.
Applicable to PET data collected on hybrid platform (PET/CT or PET/MRI).
Reduced radiation exposure.
No need of additional scans.
Market Summary
Positron-Emission Tomography (PET) is a nuclear...
Published: 2/20/2020
Contributor(s): Yang Lei, Xiaofeng Yang, Jonathon Nye, Hui Mao, Tian Liu, Tonghe Wang, Kristin Higgins
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RADcompass: Body Positioning Tool for Diagnostic Imaging in Radiology
Application
Color-coded decal to provide accurate and specific instructions for proper body positioning during radiology imaging.
Key Benefits
Saves time with each procedure.
Reduces patient exposure to unwanted radiation.
Can be used in all exams that are requested in the upright position.
Eliminate costly and time-consuming re-takes.
Relies...
Published: 1/23/2020
Contributor(s): Jason Smitherman
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Real-time, Particle-Tracking and Control Software for Electromagnetic Tweezers
Application
Software to control electromagnetic tweezers and to track tethered particles in real-time in 3D.
Key Benefits
Electromagnets offer improved temporal response without mechanical vibration.
3D particle tracking utilizing a continuous LUT built from multidimensional spline fits of discrete data improves accuracy and provides precision...
Published: 1/14/2020
Contributor(s): Daniel Kovari, David Dunlap, Laura Finzi
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High-Resolution Field Inhomogeneity Correction for Magnetic Resonance Spectroscopy
Application
Post-processing algorithm to correct field inhomogeneity in MR spectroscopy.
Key Benefits
Subvoxel field inhomogeneity correction enables CEST magnetic resonance imaging (MRI) Z-spectrum from body tissues where shimming is challenging.
Intravoxel field inhomogeneity correction enables MR spectroscopy (MRS) and MR spectroscopy imaging...
Published: 1/13/2020
Contributor(s): Zhe Phillip Sun
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Web based Software for Whole-Brain Spectroscopic MRI in Patients with Neuropathologies (BrICS)
Application
Web-based application for visualizing and analyzing spectroscopic MRI data (sMRI, MRSI) in diagnosing, treatment planning, and monitoring of neuropathologies such as tumor.
Key Benefits
Enables the analysis of multiple diagnostic images simultaneously.
Generates a heat map of metabolite (e.g., CHO/NAA) levels to better diagnose malignancies.
Incorporates...
Published: 11/30/2018
Contributor(s): Hyunsuk Shim, Saumya Gurbani, Lee Cooper, Andrew Maudsley, Sulaiman Sheriff
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Emory UniversityOffice of Technology Transfer