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Precursor PET Compound for Imaging Infections
Application Diagnostic molecules for detecting bacterial infections using nuclear imaging. Key Benefits May improve the detection of infections within the body. Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers. Market Summary The rising incidences of bacterial infections resistant...
Published: 12/20/2022       Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska
Liquid-hydrogel Hybrid Microfluidic Device
Application Measurement device for detecting of single-cell dynamics under environment perturbations or drug treatment. Key Benefits Fast determination of drug sensitivity. Long-term continuous cell-fate tracking. Time-lapse analysis of cell proliferation. Cell community analysis: intra-species interactions, inter-species interactions. Market...
Published: 12/20/2022       Contributor(s): Kyle Allison, Xin Fang, Devina Puri
Integration of Fluoroscopy Venogram and Myocardial Perfusion SPECT Image with Left-ventricular Contraction Sequence and Scar Distribution
Application 3D SPECT/venogram analysis software for optimal placement of the LV lead used in cardiac resynchronization therapy (CRT). Key Benefits Integrating widely available myocardial perfusion SPECT imaging with fluoroscopy venogram accurately visualize the targeted myocardial wall. The model incorporates LV contraction sequence and scar distribution...
Published: 12/6/2022       Contributor(s): Ji Chen
Automated Breast Arterial Calcifications Segmentation and Quantification on Mammograms Using Deep Learning
­ Application Software for the quantification of breast arterial calcifications on routine mammograms to be used for risk stratification for cardiovascular outcomes. Key Benefits Optimized image segmentation accuracy with reduced software complexity. Integrated calcium scoring. Screens patients who would not normally be indicated for cardiac...
Published: 9/29/2022       Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Xiaoyuan Guo
Quantitative Multi Energy Computed Tomography (MECT) for the Characterization of Composition and Density Maps of Artificial and Human Materials in Proton Therapy
­ Application A novel multi-energy computed tomography (MECT) simulation framework to determine the densities of human tissues and material compositions of implant material maps for proton Monte Carlo does performs the calculation. Key Benefits Provides a multi-image computer tomography based alternative methodology of providing complete maps...
Published: 12/6/2022       Contributor(s): Liyong Lin, Chih-Wei Chang, Tiezhi Zhang, Shuai Leng, Serdar Charyyev, Xiaofeng Yang, Joseph (Joe) Harms
Imaging and Tracking mRNA in Live Mammalian Cells via Fluorogenic Photoaffinity Labeling
­ Application An improved method for labeling and imagine RNA in live cells. Key Benefits Low background signal. Covalent binding suitable for time-resolved investigations. Photoactivatable for temporal control. Market Summary Ribonucleic acid (RNA) molecules are synthesized in cells through highly regulated biogenesis pathways, and when...
Published: 9/29/2022       Contributor(s): Tewoderos Ayele, Jennifer Heemstra
Multiple Organ Localization and Segmentation for Automatic Treatment Planning
­ Application A software for automatic detecting and segmenting tumors and Organs at Risk (OAR) in medical images. Key Benefits Automatically detect and segment tumors and OARs. Can detect multiple organs and generate their contour maps. Market Summary Radiation therapy (RT) is one of the most common treatment modalities for cancer and...
Published: 8/26/2022       Contributor(s): Xiaofeng Yang, Yang Lei, Tian Liu
Polydimethylsiloxane (PDMS) as a Replacement Substrate for Live Cell Imaging and UV Microscopy
­ Application Visualize cells and tissues utilizing UV microscopy. Key Benefits Low cost. Quick diagnostic for blood cultures especially for cancer diagnosis or Sickle cell anemia. Ability to visualize live cells and tissues via UV microscopy. Label and fixative free. Market Summary Polydimethylsiloxane (PDMS) is a silicon-based organic...
Published: 12/20/2022       Contributor(s): Evelyn Kendall Williams, Wilbur Lam, Ashkan Ojaghi, Francisco Robles
Software to Correct 4D CT Scan Image Distortion
Application A software that employs unsupervised deep learning to correct 4D CT scan image distortion due to respiratory motions. Key Benefits Allows the generation of highly precise, motion-corrected 4D CT images Market Summary CT scans usually allow radiation oncologists to contour a tumor’s area and position. However, abdominal motions...
Published: 8/9/2022       Contributor(s): Yang Lei, Tian Liu, Xiaofeng Yang, Yabo Fu
Low Dose PET/MRI and PET/CT Imaging
Application A deep-learning based method for generating diagnostic-quality PET images from lower quality images to reduce scanning time and radiation exposure Key Benefits Generates a high quality synthetic high-count PET image from low-count PET image or CT scan image Reduces radiation exposure to patient Reduces scanning time Market Summary Positron...
Published: 8/9/2022       Contributor(s): Xiaofeng Yang, Yang Lei, Hui Mao, Tian Liu, Jonathon Nye, Xue (Xueyuan) Dong
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