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Assessment of Tumor Response to Treatment Using Level Set Clustering in PET Images
Application
Tumor response algorithm that corrects for anatomical changes and robustly identifies local changes in serial PET images through a clustering algorithm.
Key Benefits
Robust to noise and outliers and can tolerate imperfections in data acquisition.
Could be applicable to many other imaging modalities in radiation therapy.
More accurately...
Published: 8/22/2024
Contributor(s): Timothy Fox, Eduard Schreibmann
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CXCR4-Targeting Molecules for Tumor Metastasis and PET Imaging
Application
Positron emission tomography (PET) imaging agents with high specificity for metastatic cancer.
Key Benefits
18F-labeled CXCR4 (partial) antagonist without stem cell mobilizing property is safe to be given to patient multiple times.
Identifies tumor location non-invasively and provides an indication of tumor’s metastatic potential.
Market...
Published: 11/20/2024
Contributor(s): Hyunsuk Shim, Mark Goodman, Dinesh Shetty, Yoon Hyeun Oum
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Multimodal Identification of Atrial Fibrillation Recurrence Sites
Application
Identifies areas of interest associated with atrial fibrillation recurrences.
Key Benefits
Identifies sites associated with recurrences for AF patients.
Predict AF recurrence risk in patients’ post-catheter ablation.
Development of prediction model by extracting features from the surface of interest (SOI).
Market Summary
Atrial...
Published: 11/20/2024
Contributor(s): Abhishek Midya, Anant Madabhushi, Golnoush Asaeikheybari, Mina K. Chung, Amogh Hiremath, Moore Benjamin Shoemaker, Majd A. El-Harasis, John Barnard, Rod S. Passman
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Precursor PET Compound for Imaging Infections
Application
Diagnostic molecules for detecting bacterial infections using nuclear imaging.
Key Benefits
May improve the detection of infections within the body.
Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers.
Market Summary
The rising incidences of bacterial infections resistant...
Published: 11/20/2024
Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska
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Liquid-hydrogel Hybrid Microfluidic Device
Application
Measurement device for detecting of single-cell dynamics under environment perturbations or drug treatment.
Key Benefits
Fast determination of drug sensitivity.
Long-term continuous cell-fate tracking.
Time-lapse analysis of cell proliferation.
Cell community analysis: intra-species interactions, inter-species interactions.
Market...
Published: 10/17/2024
Contributor(s): Kyle Allison, Xin Fang, Devina Puri
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Automated Breast Arterial Calcifications Segmentation and Quantification on Mammograms Using Deep Learning
Application
Software for the quantification of breast arterial calcifications on routine mammograms to be used for risk stratification for cardiovascular outcomes.
Key Benefits
Optimized image segmentation accuracy with reduced software complexity.
Integrated calcium scoring.
Screens patients who would not normally be indicated for cardiac...
Published: 7/30/2024
Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Xiaoyuan Guo
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Quantitative Multi Energy Computed Tomography (MECT) for the Characterization of Composition and Density Maps of Artificial and Human Materials in Proton Therapy
Application
A novel multi-energy computed tomography (MECT) simulation framework to determine the densities of human tissues and material compositions of implant material maps for proton Monte Carlo does performs the calculation.
Key Benefits
Provides a multi-image computer tomography based alternative methodology of providing complete maps...
Published: 7/30/2024
Contributor(s): Liyong Lin, Chih-Wei Chang, Tiezhi Zhang, Shuai Leng, Serdar Charyyev, Xiaofeng Yang, Joseph (Joe) Harms
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Imaging and Tracking mRNA in Live Mammalian Cells via Fluorogenic Photoaffinity Labeling
Application
An improved method for labeling and imagine RNA in live cells.
Key Benefits
Low background signal.
Covalent binding suitable for time-resolved investigations.
Photoactivatable for temporal control.
Market Summary
Ribonucleic acid (RNA) molecules are synthesized in cells through highly regulated biogenesis pathways, and when these...
Published: 10/28/2024
Contributor(s): Tewoderos Ayele, Jennifer Heemstra
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Multiple Organ Localization and Segmentation for Automatic Treatment Planning
Application
A software for automatic detecting and segmenting tumors and Organs at Risk (OAR) in medical images.
Key Benefits
Automatically detect and segment tumors and OARs.
Can detect multiple organs and generate their contour maps.
Market Summary
Radiation therapy (RT) is one of the most common treatment modalities for cancer and...
Published: 7/30/2024
Contributor(s): Xiaofeng Yang, Yang Lei, Tian Liu
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Polydimethylsiloxane (PDMS) as a Replacement Substrate for Live Cell Imaging and UV Microscopy
Application
Visualize cells and tissues utilizing UV microscopy.
Key Benefits
Low cost.
Quick diagnostic for blood cultures especially for cancer diagnosis or Sickle cell anemia.
Ability to visualize live cells and tissues via UV microscopy.
Label and fixative free.
Market Summary
Polydimethylsiloxane (PDMS) is a silicon-based organic...
Published: 9/26/2024
Contributor(s): Evelyn Kendall Williams, Wilbur Lam, Ashkan Ojaghi, Francisco Robles
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