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Frog Skin Peptides for Treatment of Human Influenza Viruses
Application
A therapeutic peptide that treats Influenza A virus
Key Benefits
New method of action compared to antiviral drugs currently in use.
Therapeutic peptide is virucidal against drug resistant strains.
Market Summary
Worldwide seasonal influenza epidemics can impact 5 – 15% of the population. The occurrence of vaccine mismatch...
Published: 7/30/2024
Contributor(s): Joshy Jacob, David Holthausen, Song Lee, Sanil George
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Frog Skin Peptides for Treatment of Zika Viruses
Application
A therapeutic peptide that treats Zika Virus.
Key Benefits
Potential therapeutic to fight against the growing threat of the Zika virus.
Peptide is fast acting and destroys Zika virions within 5 minutes of exposure.
Market Summary
Zika is an infectious disease spread primarily by Aedes mosquitoes and results in symptoms similar to...
Published: 11/20/2024
Contributor(s): Joshy Jacob, Song Lee, David Holthausen, Sanil George
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Granulin for Treatment of Neurodegeneration
Application
Granulin proteins (GRNs) as potential therapeutics for multiple neurodegenerative disorders caused by lysosome dysfunction and inflammation.
Key Benefits
Novel pathway and target provides new route for treatment.
Granulins shown to rescue lysosomal defects in cell culture models.
Market Summary
Granulins are small proteins that...
Published: 11/20/2024
Contributor(s): Thomas Kukar, Christopher Holler, Georgia Taylor
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Repurposed Kinase Inhibitor for Treatment of Multidrug Resistant Tuberculosis
ApplicationProtein tyrosine kinase inhibitor (imatinib) used as a treatment to prevent multiple drug-resistant tuberculosis lethality and latent reactivation.Key BenefitsEffective against drug resistant strains of tuberculosis.May be used in combination with current first-line treatments of TB.Market SummaryTuberculosis (TB) is a chronic infectious...
Published: 10/28/2024
Contributor(s): Daniel Kalman
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Progesterone Shows Promise in Treating CNS Tumors
ApplicationTreatment for neuroblastoma and other tumors in the central nervous system.Key BenefitsInduces cell death in tumor cells while having no negative effects on surrounding neurons. Slows the rate of neuroblastoma tumor growth. Technical SummaryEmory researchers have shown that progesterone caused significant cell death in tumor cells while remaining...
Published: 10/17/2024
Contributor(s): Donald Stein, Iqbal Sayeed, Fahim Atif
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