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Automated Software to Quantify Breast Arterial Calcifications from Mammograms
Application
Deep learning software for the automated detection and quantification of breast arterial calcifications in screening mammograms.
Key Benefits
Optimized image segmentation accuracy with improved generalizability towards mammograms with and without BAC presence.
Robust ability to quantitate narrow or heavy BAC and/or partial depositions...
Published: 11/20/2024
Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Aisha Urooj Khan, Theodorus Dapamede
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Vaccine-pulsed Dendritic Cells as a Treatment for Aggressive Breast Cancers
Application
Immunotherapy for HER2+ and triple-negative breast cancer.
Key Benefits
Autologous vaccine comprising patient-specific tumor antigens and immune stimulatory components against aggressive breast cancers.
Prepared outside of the body and then administered to patients.
Preclinical data indicate treatment decreases tumor growth and improves...
Published: 10/17/2024
Contributor(s): Periasamy (Selva) Selvaraj, Luis Munoz, Ramireddy Bommireddy, Christopher Pack, Shaker Reddy, Sampath Ramachandiran
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Automated Breast Arterial Calcifications Segmentation and Quantification on Mammograms Using Deep Learning
Application
Software for the quantification of breast arterial calcifications on routine mammograms to be used for risk stratification for cardiovascular outcomes.
Key Benefits
Optimized image segmentation accuracy with reduced software complexity.
Integrated calcium scoring.
Screens patients who would not normally be indicated for cardiac...
Published: 7/30/2024
Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Xiaoyuan Guo
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Biodegradable Nanoparticle Encapsulating Anti-Cancer Drug for the Treatment of Therapy-Resistant Cancers
Application
A targeted polymeric nanoparticle drug that inhibits NADPH Oxidase (NOX1/4)-Reactive oxygen species (ROS) signal for the treatment of chemotherapy drug and radiotherapy resistant cancers.
Key Benefits
Inhibits tumor growth.
Dual chemo-and radiotherapy enhancer.
Excellent biocompatibility and stability.
CD44 targeted drug delivery...
Published: 11/20/2024
Contributor(s): Lily Yang, Lei Zhu
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Obstrix: Inflatable Cerclage Pessary
Application
Expandable cervical pessary device to treat cervical incompetence.
Key Benefits
Inflatable device can adapt to any size.
Eliminates need for sutures or cervical tape, reducing risk of cervical trauma.
Market Summary
Cervical incompetence is a premature dilation and effacement (cervical ripening) during the second trimester of pregnancy...
Published: 7/30/2024
Contributor(s): Robert Kelley, Sruti Bheri, Esther Max-Onakpoya, Xiaoshan (Melody) Shao, Alena Sim
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MOMVAX (TM) P3 (TM)
ApplicationComprehensive education package that includes iPad app and website focused on increasing influenza and pertussis vaccinations among pregnant women.Key BenefitsProvides a comprehensive educational package for patients as well as healthcare providers. Is founded on an evidence-based educational system. Market SummarySignificantly more people...
Published: 11/20/2024
Contributor(s): Saad Omer, Allison Abramson, Walter Orenstein, Paula Frew, Katy Seib
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