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Questionnaires for Assessing the Effect of Visual Impairment on Quality of Life and Function in Children
Application
A standardized series of questions for the assessment of vision related quality of life and visual function in children and adolescents.
Key Benefits
Provides age-appropriate questions for children from ages 8-18 as an improvement to using currently available assessments geared toward adults.
Allows the subjective assessment of the...
Published: 4/23/2024
Contributor(s): Sheila Angeles-Han
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Vision Test for Non-Verbal Children
Application
Vision testing for non-verbal children, the hearing impaired, and non English-speaking population.
Key Benefits
Simplifies vision testing for non-verbal children.
Does not require any verbal communication to be used effectively.
Technical Summary
While traditional eye charts are often effective, they rely on verbal communication...
Published: 4/23/2024
Contributor(s): Amy Hutchinson, Caroline Cromelin, Cindy Harrington
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Surgical Device for Eyelid Ptosis Correction
ApplicationSurgical device to perform clamping, incision, and closure for correcting eyelid ptosis.Key BenefitsSimplifies the Müller muscle resection that decreases surgical procedure time.Eliminates the risk of cutting sutures that cause dehiscence and improves the final appearance.Market SummaryPtosis (drooping upper eyelids) is a common condition...
Published: 4/23/2024
Contributor(s): Denise Kim, Jacquelyn Borinski, Andrew Kolpitcke, Mohamad Ali Naja, Drew Padilla
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Knock-In Mouse Model of Oculopharyngeal Muscular Dystrophy
ApplicationConditional knock-in mouse mimicking Oculopharyngeal muscular dystrophy.Technical SummaryOculopharyngeal muscular dystrophy (OPMD) is rare genetic disease caused by a mutation in the PABPN1 gene. In this mutation, the number of GCG trinucleotide repeats at the 5' end of PABPN1 are increased, which leads to an expansion of an alanine repeat...
Published: 4/23/2024
Contributor(s): Grace Pavlath, Anita Corbett, Katherine Vest
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Treatment of Dry AMD and Other Ophthalmic Diseases
Application
Fulvene and fulvalene compounds that inhibit nicotinamide adenine dinucleotide phosphate (NADPH) oxidases for the treatment of ophthalmic diseases and disorders including the dry form of age-related macular degeneration.
Key Benefits
Lead compound candidate identified.
Demonstrated positive effects in in vivo preclinical ocular models...
Published: 4/23/2024
Contributor(s): Jack Arbiser
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Training Device to Improve Physician Microlaryngeal Surgical Dissection
Application
Training device that simulates the human vocal fold (SVF) is designed to assist in the development of fine manual dexterity and instrument precision necessary for physicians to perform microlaryngeal surgical dissection.
Key Benefits
The SVF housed within a plastic larynx model approximates the both the delicate tissue and limited operating...
Published: 4/23/2024
Contributor(s): Michael Johns Iii, Adam Klein
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