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Imaging and Tracking mRNA in Live Mammalian Cells via Fluorogenic Photoaffinity Labeling
Application
An improved method for labeling and imagine RNA in live cells.
Key Benefits
Low background signal.
Covalent binding suitable for time-resolved investigations.
Photoactivatable for temporal control.
Market Summary
Ribonucleic acid (RNA) molecules are synthesized in cells through highly regulated biogenesis pathways, and when these...
Published: 2/13/2025
Contributor(s): Tewoderos Ayele, Jennifer Heemstra
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A Method of Using Responsive Micro and Sub-micro Scale Polymer Particles for Mechanical Manipulation of Molecules
Application
A method to study the mechanical/controlled unfolding of biomolecules using a polymer force clamp (PFC).
Key Benefits
Particles can be immobilized onto virtually any type of support.
Particles can also be functionalized with a variety of small-molecule, peptide and protein ligands.
Ability to have multiple PFC’s measuring associated...
Published: 10/28/2024
Contributor(s): Hanquan Su, Khalid Salaita
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tPAINT to Measure Molecular Forces in Live Cells
Application
DNA-based probes to measure the nanoscale distribution of piconewton molecular forces in live cells.
Key Benefits
Provides maps of integrin tension with up to ˜25 nm resolution and piconewton force sensitivity for live-cell imaging.
The tPAINT can be performed on a commercial TIRF microscope.
Market Summary
Emory inventors...
Published: 2/13/2025
Contributor(s): Joshua Brockman, Hanquan Su, Khalid Salaita
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Psychosis Prediction Using Speech Patterns
Application
Linguistic software to predict and diagnose psychosis.
Key Benefits
New method of diagnosing psychosis.
Very high accuracy rate (86.7%).
Market Summary
Psychotic disorders are mental illnesses characterized by delusions, hallucinations, and disorganized thinking and speaking. Schizophrenia is an example of a psychotic disorder....
Published: 7/30/2024
Contributor(s): Phillip Wolff, Jinho Choi
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Study Management and Retention Toolkit (SMART)
ApplicationMobile app and desktop application for management of research studies involving human patients.Key BenefitsSupports a variety of study formats.Combines management of all parts of study in one place.Automatically reminds patients and research staff of upcoming appointments and tasks.Improves communication between study admin and study participants.Market...
Published: 10/28/2024
Contributor(s): Eli Rosenberg, Patrick Sullivan
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EasyOocyte: Software for Recording Digital Record from Xenopus Laevis Oocytes
ApplicationSoftware to automate drug application and data collection for recording from Xenopus oocytes.Key BenefitsEnables automation of pharmacological experiments.Improves the efficiency of research and pharmaceutical drug development.Technical SummaryEmory University researchers have developed software to increase the efficiency of electrophysiological...
Published: 10/17/2024
Contributor(s): Stephen Traynelis, Kevin Ogden
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OSIRIS: An Information Management Application for Use in Drug Discovery and Development
Application
A web-based information management application for data tracking and sharing during the discovery and development of new small molecule therapeutics.
Key Benefits
Can be used to register compounds and display information about chemical structures and calculations.
Easily customizable and has a ticket system to allow administrators...
Published: 2/13/2025
Contributor(s): Serdar Kurtkaya, Iestyn Lewis, Michael Natchus, James Snyder
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Automatic Mouse Movement Analysis Enhances Web Advertising
Application
Browser mouse monitoring algorithms for improved targeting of web
advertisement to client needs.
Key Benefits
Novel integration of client side instrumentation and server side
information.
Detects misleading information that otherwise misclassifies client
intent.
Technical Summary
Software has been developed that combines...
Published: 2/13/2025
Contributor(s): Yevgeny (Eugene) Agichtein, Qi Guo
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