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Theranostic Biomarker for Aspirin-Exacerbated Respiratory Disease
Application
Biomarkers for a clinical diagnostic tool and non-psychogenic therapy to detect and treat aspirin-exacerbated respiratory disease.
Key Benefits
Does not rely on aspirin challenge, increasing safety and availability for suspected patients.
May be used in patients who have respiratory compromise or are not stable.
Minimally-invasive...
Published: 9/26/2024
Contributor(s): Joshua Levy, Samuel Molina
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Targeting Peptide Improves Accurate Myocarditis Imaging and Diagnosis
ApplicationTargeting peptide molecule for image-based diagnosis of myocarditis.Key BenefitsEnables noninvasive diagnosis of myocarditis.Targets and binds to biomarker of myocarditis.Market SummaryMyocarditis is an inflammation of the heart muscle (myocardium). Myocarditis can affect your heart muscle and your heart's electrical system, reducing the...
Published: 7/30/2024
Contributor(s): Michael E. Davis, Mario Martinez
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Bioluminescent Ion Indicator Proteins
ApplicationFusion protein for non-invasive assessment of chloride fluctuations in neuronal processes.Key BenefitsEnables a non-invasive method of imaging chloride in animals.Offers high signal-to-noise ratio compared to fluorescent light.Market SummaryNeuronal chloride (Cl-) is involved in many normal neurophysiological activities, including synaptic...
Published: 11/20/2024
Contributor(s): Robert E. Gross, Ken Berglund, Jack Tung
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Compound and Method to Explore and Prepare O-Glycans from Living Cells
ApplicationChemical compound and method that enables detection of O-glycans with higher sensitivity than conventional approaches.Key BenefitsHigher accuracy and sensitivity than current β-elimination method.Smaller sample quantities required compared to traditional mass spectrometry.Method promotes the discovery of novel glycans and study of cellular...
Published: 9/26/2024
Contributor(s): Tongzhong Ju, Richard Cummings, Matthew Kudelka
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Oxidative Stress Markers May Predict Atrial Fibrillation Onset
Application
Diagnostic test for predicting the onset of atrial fibrillation (AF).
Key Benefits
Potential diagnostic test to predict susceptibility to arrhythmia.
Extensive (100kb) of SCN5A promoter sequence has been identified.
Technical Summary
The invention provides oxidative stress blood markers for use in predicting the onset of atrial...
Published: 12/4/2024
Contributor(s): Dean Jones, Samuel Dudley
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