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Automated Software to Quantify Breast Arterial Calcifications from Mammograms
Application Deep learning software for the automated detection and quantification of breast arterial calcifications in screening mammograms. Key Benefits Optimized image segmentation accuracy with improved generalizability towards mammograms with and without BAC presence. Robust ability to quantitate narrow or heavy BAC and/or partial depositions...
Published: 4/11/2024       Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Aisha Urooj Khan
Vaccine-pulsed Dendritic Cells as a Treatment for Aggressive Breast Cancers
Application Immunotherapy for HER2+ and triple-negative breast cancer. Key Benefits Autologous vaccine comprising patient-specific tumor antigens and immune stimulatory components against aggressive breast cancers. Prepared outside of the body and then administered to patients. Preclinical data indicate treatment decreases tumor growth and improves...
Published: 4/23/2024       Contributor(s): Periasamy (Selva) Selvaraj, Luis Munoz, Ramireddy Bommireddy, Christopher Pack, Shaker Reddy, Sampath Ramachandiran
Automated Breast Arterial Calcifications Segmentation and Quantification on Mammograms Using Deep Learning
­ Application Software for the quantification of breast arterial calcifications on routine mammograms to be used for risk stratification for cardiovascular outcomes. Key Benefits Optimized image segmentation accuracy with reduced software complexity. Integrated calcium scoring. Screens patients who would not normally be indicated for cardiac...
Published: 4/24/2024       Contributor(s): Hari Trivedi, Imon Banerjee, William Charles O'Neill, Xiaoyuan Guo
Biodegradable Nanoparticle Encapsulating Anti-Cancer Drug for the Treatment of Therapy-Resistant Cancers
­ Application A targeted polymeric nanoparticle drug that inhibits NADPH Oxidase (NOX1/4)-Reactive oxygen species (ROS) signal for the treatment of chemotherapy drug and radiotherapy resistant cancers. Key Benefits Inhibits tumor growth. Dual chemo-and radiotherapy enhancer. Excellent biocompatibility and stability. CD44 targeted drug delivery...
Published: 4/23/2024       Contributor(s): Lily Yang, Lei Zhu
Obstrix: Inflatable Cerclage Pessary
Application Expandable cervical pessary device to treat cervical incompetence. Key Benefits Inflatable device can adapt to any size. Eliminates need for sutures or cervical tape, reducing risk of cervical trauma. Market Summary Cervical incompetence is a premature dilation and effacement (cervical ripening) during the second trimester of pregnancy...
Published: 4/23/2024       Contributor(s): Robert Kelley, Sruti Bheri, Esther Max-Onakpoya, Xiaoshan (Melody) Shao, Alena Sim
MOMVAX (TM) P3 (TM)
ApplicationComprehensive education package that includes iPad app and website focused on increasing influenza and pertussis vaccinations among pregnant women.Key BenefitsProvides a comprehensive educational package for patients as well as healthcare providers. Is founded on an evidence-based educational system. Market SummarySignificantly more people...
Published: 4/23/2024       Contributor(s): Saad Omer, Allison Abramson, Walter Orenstein, Paula Frew, Katy Seib