Technology Listings


63 Results Sort By:
ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to stud...
Published: 7/9/2019       Inventor(s): Erwin Van Meir
ADGRB1/BAI1 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B1, brain-specific angiogenesis inhibitor-1 (ADGRB1/BAI1) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB1/BAI1 gene. These mice were developed through homologous recombination and have LacZ gene knock-in. Mice were...
Published: 7/9/2019       Inventor(s): Erwin Van Meir
Parent-Rated Anxiety Scale for Autism Spectrum Disorder (PRAS-ASD)
ApplicationScale/survey instrument for measuring anxiety in children with autism based upon a parent report.Key BenefitsIncludes 25-item measure for anxiety.Tested in a large-scale survey and clinical setting.Market SummaryAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and repetitive b...
Published: 7/8/2019       Inventor(s): Lawrence Scahill, Luc Lecavalier, Michael Aman, Karen Bearss
Tele-Savvy: Dementia Caregiver Online Psychoeducation Program
ApplicationA web-based online program that supports and educates Alzheimer's (AD) patient's caregivers.Key BenefitsAllows remote access to the psychoeducation program when in-person training is not available.Application of online education technology provides more cost-effective self-learning modules.Market SummaryThe "Savvy Caregiver Program,...
Published: 4/29/2019       Inventor(s): Kenneth Hepburn, Patricia Griffiths
Non-Invasive Millimeter Depth Near-Infrared Monitoring System
ApplicationFrequency domain near-infrared spectroscopy (fdNIRS) system for non-invasive characterization of blood volume and tissue oxygen saturation at millimeter-scale depths.Key BenefitsNoninvasive optical method for monitoring tissue oxygen level and blood volume for brain research in small animals.Provides portable, cost-effective alternative ...
Published: 4/12/2019       Inventor(s): Erin Buckley, Seung Yup Lee
ADGRB3/BAI3-Expressing Cell Lines
ApplicationADGRB3/BAI3 expressing human brain tumor cell lines.Technical SummaryAdhesion G protein coupled receptor B3 (ADGRB3), also called Brain-specific angiogenesis inhibitor 3 (BAI3) is a protein that in humans is encoded by the ADGRB3 gene. Emory University researcher Erwin Van Meir has developed medulloblastoma cell lines DAOY, UW288-1 and P...
Published: 1/22/2019       Inventor(s): Erwin Van Meir
Granulin for Treatment of Neurodegeneration
ApplicationGranulin proteins (GRNs) as potential therapeutics for multiple neurodegenerative disorders caused by lysosome dysfunction and inflammation.Key BenefitsNovel pathway and target provides new route for treatment.Granulins shown to rescue lysosomal defects in cell culture models.Market SummaryGranulins are small proteins that are derived by...
Published: 12/18/2018       Inventor(s): Thomas Kukar
Web based Software for Whole-Brain Spectroscopic MRI in Patients with Neuropathologies (BrICS)
ApplicationWeb-based application for visualizing and analyzing spectroscopic MRI data (sMRI, MRSI) in diagnosing, treatment planning, and monitoring of neuropathologies such as tumor.Key BenefitsEnables the analysis of multiple diagnostic images simultaneously.Generates a heat map of metabolite (e.g., CHO/NAA) levels to better diagnose malignancies...
Published: 11/30/2018       Inventor(s): Hyunsuk Shim, Saumya Gurbani, Lee Cooper, Andrew Maudsley, Sulaiman Sheriff
3q29 Deletion Mice
ApplicationMouse models with the deletion of 3q29 for the study of neurological disorders such as schizophrenia, autism, and anxiety disorders.Technical SummaryCopy Number Variants (CNV’s) are large genomic deletion or duplications. One of the CNV’s, the 3q29 deletion, confers more than 40 fold increase in risk of schizophrenia. Most pe...
Published: 8/23/2018       Inventor(s): Tamara Caspary, David Weinshenker, Stephen Warren
Cre-Lox PAR1 Conditional Knockout Mouse
Key BenefitsTissue-specific knockout mouse, allowing PAR1 to be inactivated in specific cell types in certain tissue.Inducible knockout mouse, allowing PAR1 to be temporally suppressed at a given time-point in embryonic, post-natal or adult animals.Eliminates drawbacks and side effects of traditional knockout processes that eliminate genes from the...
Published: 6/26/2018       Inventor(s): Stephen Traynelis
1 2 3 4 5 6 7