Technology Listings


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Clinical Decision Support System
Application Software that provides "smart phrases" or "auto text" which the clinician may employ to enhance and expedite evidence-based documentation and state-of-the-art care delivery. Key Benefits Quickly composed text that is directly inserted into a clinical note. Easily reviewable with the ability to edit text in the ...
Published: 10/11/2019       Inventor(s): Justin Cheeley
Automated Assessment of Visuospatial Memory as a Screening Tool
Application Visuospatial memory paradigm that passively assesses memory using eye movements, rather than explicit memory judgements, to detect objective memory impairment and to predict Alzheimer’s disease and cognitive status. Key Benefits Does not require verbal or written response for assessment, reducing social and cultural bias. Re...
Published: 10/11/2019       Inventor(s): Rafi Haque, Allan Levey, Gari Clifford, LaVonda Brown, Cecelia Manzanares
PET Tracer for Parkinson’s Disease Diagnostic
Application Small molecule PET tracer for Lewy bodies in the brain for diagnosing Parkinson’s Disease or other Lewy body related diseases. Key Benefits PET tracer to enable quantification of α-Syn. Improves diagnosis of Parkinson’s disease. Allows for earlier treatment. Market Summary Parkinson’s disease is a neuro...
Published: 8/26/2019       Inventor(s): Keqiang Ye
Biomarker for Clinical Prognosis for Lung Cancer Patients
Application Biomarker to predicting clinical outcome and treatment options for lung cancer patients. Key Benefits Provides early determination of prognosis. Market Summary Upon diagnosis with cancer, there are many different treatment options. While some more aggressive treatment options can be more dangerous to the patient, these aggressiv...
Published: 7/2/2019       Inventor(s): Adam Marcus, Brian Pedro, Jessica Konen
Theranostic Biomarker for Aspirin-Exacerbated Respiratory Disease
Application Biomarkers for a clinical diagnostic tool and non-psychogenic therapy to detect and treat aspirin-exacerbated respiratory disease. Key Benefits Does not rely on aspirin challenge, increasing safety and availability for suspected patients. May be used in patients who have respiratory compromise or are not stable. Minimally-invasiv...
Published: 7/2/2019       Inventor(s): Joshua Levy, Samuel Molina
Combination Therapy for Increasing Venetoclax Sensitivity in Multiple Myeloma
Application Marker and co-therapy that inhibits succinate dehydrogenase to increase patient response to venetoclax. Key Benefits Co-therapy increases MM sensitivity to venetoclax treatment. Identifies patients who will respond to venetoclax therapy. Market Summary Multiple Myeloma (MM) is a cancer of plasma cells responsible for making ant...
Published: 6/18/2019       Inventor(s): Malathy (mala) Shanmugam, Richa Bajpai
Antibodies for Zika and Dengue Viruses
ApplicationsELISAWestern BlotImmunohistochemistrySpecificityHuman monoclonalTechnical SummaryZika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion. The investig...
Published: 5/9/2019       Inventor(s): Jens Wrammert, Mark Mulligan
Glycoprotein Tetramer for Identifying Antigen-specific B Cells
ApplicationEctodomain of viral glycoprotein tetramers detects antigen-specific memory B Cells.Key BenefitsViral glycoprotein tetramers detect antigen-specific memory B cells in the peripheral blood and tissues.Hepatitis C virus E2 protein triggers immune response, which may yield an effective vaccine against hepatitis C virus.Market SummaryHepatiti...
Published: 5/9/2019       Inventor(s): Arash Grakoui, Joseph Marcotrigiano
Granulin for Treatment of Neurodegeneration
ApplicationGranulin proteins (GRNs) as potential therapeutics for multiple neurodegenerative disorders caused by lysosome dysfunction and inflammation.Key BenefitsNovel pathway and target provides new route for treatment.Granulins shown to rescue lysosomal defects in cell culture models.Market SummaryGranulins are small proteins that are derived by...
Published: 12/18/2018       Inventor(s): Thomas Kukar
Ebola Specific Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) Assay
ApplicationA cell based assay to quantify the titer of circulating Ebola glycoprotein (GP) antibodies that trigger antibody-dependent cell-mediated cytotoxicity (ADCC).Key BenefitsSpecific for detection of ADCC activity of Ebola virus antibodies or antisera.Applicable to all pathogenic strains of Ebola virus.Ebola GP-specific stable reporter cells ...
Published: 11/26/2018       Inventor(s): Paul Spearman, Karnail Singh, Xuemin Chen
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