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Questionnaires for Assessing the Effect of Visual Impairment on Quality of Life and Function in Children
Application A standardized series of questions for the assessment of vision related quality of life and visual function in children and adolescents. Key Benefits Provides age-appropriate questions for children from ages 8-18 as an improvement to using currently available assessments geared toward adults. Allows the subjective assessment of the...
Published: 3/1/2024       Contributor(s): Sheila Angeles-Han
Vision Test for Non-Verbal Children
Application Vision testing for non-verbal children, the hearing impaired, and non English-speaking population. Key Benefits Simplifies vision testing for non-verbal children. Does not require any verbal communication to be used effectively. Technical Summary While traditional eye charts are often effective, they rely on verbal communication...
Published: 7/28/2023       Contributor(s): Amy Hutchinson, Caroline Cromelin, Cindy Harrington
Surgical Device for Eyelid Ptosis Correction
ApplicationSurgical device to perform clamping, incision, and closure for correcting eyelid ptosis.Key BenefitsSimplifies the Müller muscle resection that decreases surgical procedure time.Eliminates the risk of cutting sutures that cause dehiscence and improves the final appearance.Market SummaryPtosis (drooping upper eyelids) is a common condition...
Published: 7/28/2023       Contributor(s): Denise Kim, Jacquelyn Borinski, Andrew Kolpitcke, Mohamad Ali Naja, Drew Padilla
Knock-In Mouse Model of Oculopharyngeal Muscular Dystrophy
ApplicationConditional knock-in mouse mimicking Oculopharyngeal muscular dystrophy.Technical SummaryOculopharyngeal muscular dystrophy (OPMD) is rare genetic disease caused by a mutation in the PABPN1 gene. In this mutation, the number of GCG trinucleotide repeats at the 5' end of PABPN1 are increased, which leads to an expansion of an alanine repeat...
Published: 12/1/2023       Contributor(s): Grace Pavlath, Anita Corbett, Katherine Vest
Treatment of Dry AMD and Other Ophthalmic Diseases
Application Fulvene and fulvalene compounds that inhibit nicotinamide adenine dinucleotide phosphate (NADPH) oxidases for the treatment of ophthalmic diseases and disorders including the dry form of age-related macular degeneration. Key Benefits Lead compound candidate identified. Demonstrated positive effects in in vivo preclinical ocular models...
Published: 7/28/2023       Contributor(s): Jack Arbiser
Training Device to Improve Physician Microlaryngeal Surgical Dissection
Application Training device that simulates the human vocal fold (SVF) is designed to assist in the development of fine manual dexterity and instrument precision necessary for physicians to perform microlaryngeal surgical dissection. Key Benefits The SVF housed within a plastic larynx model approximates the both the delicate tissue and limited operating...
Published: 11/6/2023       Contributor(s): Michael Johns Iii, Adam Klein