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Breathing Training Program for COPD Patients

Application Coaching program especially tailored to teach breathing techniques to COPD patients. Key Benefits Personalized coaching program. Tracks and saves lung performance. Adapts training program to patient’s lung performance. Offers adjunct or combination to therapeutics. Improves management of COPD complications in patient’s daily life. Market...

Published: 2/20/2020 Inventor(s): Weihua Zhang

Mobile Application for COPD Patients

Application Mobile application for teaching breathing techniques to patients with chronic obstructive pulmonary disease (COPD). Key Benefits Personalized coaching program. Tracks and saves lung performance. Adapts training program to patient’s lung performance. Can be done from the comfort of the patient’s home. Market Summary Chronic obstructive...

Published: 1/22/2020 Inventor(s): Weihua Zhang

Virus-Like Particles as RSV Vaccine Candidate

Application Virus-like particle (VLP) vaccine candidate(s) to prevent respiratory syncytial virus (RSV) infection. Key Benefits Candidates may have the most effective anti-viral and anti-inflammatory response. Potentially protects elderly and immunocompromised patients from re-infection with the RSV virus. Efficient, tunable and stable production...

Published: 1/15/2020 Inventor(s): Binh Ha, Larry Anderson, Elizabeth Wright

Theranostic Biomarker for Aspirin-Exacerbated Respiratory Disease

ApplicationBiomarkers for a clinical diagnostic tool and non-psychogenic therapy to detect and treat aspirin-exacerbated respiratory disease.Key BenefitsDoes not rely on aspirin challenge, increasing safety and availability for suspected patients.May be used in patients who have respiratory compromise or are not stable.Minimally-invasive approach.Market...

Published: 7/2/2019 Inventor(s): Joshua Levy, Samuel Molina

Peptide Therapeutic for Acute Respiratory Distress Syndrome

ApplicationAnti-claudin 5 peptide to improve lung barrier function for the treatment of alcohol-induced acute respiratory distress syndrome (ARDS).Key BenefitsNew target for treating ARDS.Small inhibitory peptide to specifically target claudin-5.Market SummaryApproximately 200,000 cases of acute respiratory distress syndrome (ARDS) are diagnosed each...

Published: 5/13/2019 Inventor(s): Michael Koval, Barbara Schlingmann-Molina

Alexidine and Analogs to Treat Lung Cancer

ApplicationSmall molecule therapeutic specifically targeting invasive cancer cells for treatment of lung cancer.Key BenefitsInhibits cancer cell invasion.Utilizes a novel mechanism of action.Market SummaryLung cancer is the second most prevalent type of cancer, causing more than 150,000 deaths in the United States per year. One of the main barriers...

Published: 4/12/2019 Inventor(s): Adam Marcus, Jessica Konen, Rachel Commander, Jamie Arnst, Thota Ganesh

Respiratory Syncytial Virus Strain A2-2-20F

ApplicationStrain of respiratory syncytial virus (RSV) for vaccine and therapeutic research and development.Key BenefitsHigher early viral load.Induces greater necrotic airway damage and neurophil infiltration.Market SummaryRSV is a highly contagious and ubiquitous virus that causes respiratory tract infections in individuals of all ages, particularly...

Published: 10/16/2018 Inventor(s): Martin Moore

GeneRegs: Nanoparticles for Treatment of Severe Asthma

Application Gold nanoparticles coated with enzyme which specifically targets and degrades asthma-associated inflammation molecules. Key Benefits Specifically suppresses asthma associated inflammation. Easy self-administration by inhalation. Market Summary Asthma is defined as a chronic inflammatory lung disease with significant worldwide morbidity....

Published: 12/4/2017 Inventor(s): Khalid Salaita, Cherry Wongtrakool, Kornelia Galior

Respiratory Syncytial Virus (RSV) A2 Expressing Firefly Luciferase

ApplicationRecombinant RSV strain expressing firefly luciferase and the F & G genes from clinical strain A2001/2-20 for research and development of vaccines.Key BenefitsF & G proteins included in this strain show different behavior than those of the typical A2 strain proteins.May be adapted in a variety of assays, enabling the identification of RSV...

Published: 2/19/2017 Inventor(s): Martin Moore, Christopher Stobart

Helper Plasmids for Rescue of Respiratory Syncytial Virus

ApplicationPlasmids rescuing recombinant syncytial virus for RSV research and vaccine development.Key BenefitsAllow expression and recombination in vero cells.Optimized for human codon bios to increase expression in mammalian cells.Market SummaryRespiratory syncytial virus (RSV) is the major cause of acute lower respiratory tract infections in infants...

Published: 2/16/2017 Inventor(s): Martin Moore

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