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Ready for Tonsillectomy Mobile App
Application A child-friendly mobile application designed to educate children and caregivers on the purpose of tonsillectomies and guide them through pre-, intra-, and post-operative care using age-appropriate, interactive content. Key Benefits The app is interactive and provides education at a child’s literacy level. Market Summary Tonsillectomies...
Published: 11/7/2025       Contributor(s): Holly Cordray, Nikhila Raol, Kara Prickett
Pediatric Autism Insomnia Rating Scale (PAIRS)
Application Brief parent rating scale for researchers and clinicians to evaluate insomnia severity in children with autism spectrum disorder (ASD) age 3 to 12 years. Key Benefits Concise 21-question rating scale for caregivers of children with ASD. Internally consistent and reliable across severity levels. Highly correlated with existing tests. Usable...
Published: 10/15/2025       Contributor(s): Lawrence Scahill, Luc Lecavalier, Cynthia R. Johnson, Michael C. Edwards
Function-Based Elopement Intervention Manual
Application A manualized intervention for the assessment and treatment of elopement for autistic youth. Key Benefits Provides clear step-by-step instructions/guidance for clinicians to coach caregivers. Employs specific strategies to reduce elopement incidents, minimize safety risks, and enforce readiness response. Parents and therapists find...
Published: 10/6/2025       Contributor(s): Mindy Scheithauer, Sarah Slocum Freeman, Nathan (Nate) Call, Joanna E. Mevers, Colin Muething, Lawrence Scahill
Questionnaires for Assessing the Effect of Visual Impairment on Quality of Life and Function in Children
Application A standardized series of questions for the assessment of vision related quality of life and visual function in children and adolescents. Key Benefits Provides age-appropriate questions for children from ages 8-18 as an improvement to using currently available assessments geared toward adults. Allows the subjective assessment of the...
Published: 2/13/2025       Contributor(s): Sheila Angeles-Han
Drug Platform for L-Asparaginases for the Treatment of Leukemias
Application A novel humanized therapeutic L-asparaginase compound to treat acute lymphoblastic leukemia (ALL) and other cancers. Key Benefits A novel drug discovery platform for developing asparaginase-based compounds to treat leukemias and other cancers. The derivatives could exhibit less immunogenicity and systemic toxicity than FDA-approved...
Published: 11/12/2025       Contributor(s): Sunil Raikar, Christopher Doering, H. (Harold) Trent Spencer, Kristopher Knight, Harrison Brown
RSV Vaccine for Infants and Children
Application Vaccine for Respiratory Syncytial Virus (RSV) in infants and children. Key Benefits A novel vaccine targeting both the F and G proteins of the respiratory syncytial virus (RSV), including its variants. Preliminary data in in mice show the vaccine induced the production of antibodies associated with preventing disease. Potential to...
Published: 2/13/2025       Contributor(s): Larry Anderson, Binh Ha, Heying Sun
Non-invasive Probes to Determine Efficacy of Cancer Therapies
Application A real-time, non-invasive probe to determine the efficacy of cancer immunotherapies. Key Benefits Determines immunotherapy success in patients. CAR cells can be tested before putting it back in the patients. Simple diagnostic with readout in 30 minutes compared to 2-3 days. Market Summary Lymphoblastic leukemia is one of the most...
Published: 9/22/2025       Contributor(s): Anna Kellner, Khalid Salaita, Curtis Henry
Improving Pediatric Asthma Management for Urban Families
Application Home-based family psychoeducational intervention for low-income children with persistent asthma. Key Benefits Medical and psychosocial needs of patients and family members can be addressed simultaneously. Significantly improved asthma management and caregiver stress in randomized controlled clinical trial. Market Summary Asthma...
Published: 2/13/2025       Contributor(s): Marianne Celano, Lisa Kobrynski, Chanda Holsey
Engineered Biomaterials for Vascular Grafts
Application A biomaterial to create grafts for treating babies with congenital heart diseases. Key Benefits A biocompatible material that can be used to reroute blood within the body. Experimental data in animals show the material is biocompatible with no clots, thrombus, or adverse immune reactions. Potential to be used in other cardiovascular...
Published: 2/13/2025       Contributor(s): Saimuralidhar (Murali) Padala, Jahnavi Mudigonda
Central Line-Associated Bloodstream Infection (CLABSI) Prediction Model
­ Application A predictive model of central line-association bloodstream infection (CLABSI). Key Benefits Specifically designed to improved predictive analysis of patients who are at risk for CLABSI. Scored higher predictive values on average than similar predictive modeling without the hypotheses driven approach (Bidirectional LSTM with...
Published: 2/13/2025       Contributor(s): Azade Tabaie, Rishikesan (Rishi) Kamaleswaran, Evan Orenstein
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