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Microfluidic Device Enhances Understanding of Clot Formation
Application A microfluidic device for the measurement and quantification of the mechanical forces that occur during clot formation for use in hematology research or for diagnostic purposes. Key Benefits Is capable of measuring platelet-platelet interactions at the single cell level that is not possible with current tools. Facilitates quick &...
Published: 11/20/2024       Contributor(s): David Myers, Wilbur Lam, Yongzhi Qiu
Repurposed Antifibrinolytic Agents as a Substitute for Platelet Transfusions to Prevent Bleeding in Severe Thrombocytopenia Patients
Application Prophylactic administration of an antifibrinolytic agent, epsilon aminocaproic acid (EACA), to prevent bleeding in patients with thrombocytopenia from hematological malignancies. Key Benefits Orally bioavailable, repurposed drug. Commonly used and FDA approved to manage hemorrhage in patients with congenital bleeding. Cheaper and...
Published: 9/26/2024       Contributor(s): Hanna Khoury, Ana Antun