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Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application
Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations.
Key Benefits
Tunable oligos increase specificity and cooperative binding to the disease target of interest.
Distinguishes between cis- and trans mutations.
Identifies different strains of...
Published: 3/1/2024
Contributor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt
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Improved Clinical Diagnostic Method for SARS-CoV-2 Infection
Application
A more reliable and accurate method for diagnosing SARS-CoV-2 infection based on the biochemical interactions between the spike trimer and ACE-2 protein.
Key Benefits
A fast, affordable, and easy-to-use SARS-Cov-2 diagnostic test for use in clinical settings.
Market Summary
SARS-CoV-2 has evolved significantly since the onset of...
Published: 11/27/2023
Contributor(s): John Roback, Andrew Neish, Narayanaiah Cheedarla, Hans Verkerke, Huixia Wu, William Osick, Kaleb Mclendon, Sindhu Potlapalli
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Precursor PET Compound for Imaging Infections
Application
Diagnostic molecules for detecting bacterial infections using nuclear imaging.
Key Benefits
May improve the detection of infections within the body.
Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers.
Market Summary
The rising incidences of bacterial infections resistant...
Published: 4/23/2024
Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska
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