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Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations. Key Benefits Tunable oligos increase specificity and cooperative binding to the disease target of interest. Distinguishes between cis- and trans mutations. Identifies different strains of...
Published: 5/21/2024       Contributor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt
Improved Clinical Diagnostic Method for SARS-CoV-2 Infection
Application A more reliable and accurate method for diagnosing SARS-CoV-2 infection based on the biochemical interactions between the spike trimer and ACE-2 protein. Key Benefits A fast, affordable, and easy-to-use SARS-Cov-2 diagnostic test for use in clinical settings. Market Summary SARS-CoV-2 has evolved significantly since the onset of...
Published: 11/27/2023       Contributor(s): John Roback, Andrew Neish, Narayanaiah Cheedarla, Hans Verkerke, Huixia Wu, William Osick, Kaleb Mclendon, Sindhu Potlapalli
Precursor PET Compound for Imaging Infections
Application Diagnostic molecules for detecting bacterial infections using nuclear imaging. Key Benefits May improve the detection of infections within the body. Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers. Market Summary The rising incidences of bacterial infections resistant...
Published: 4/23/2024       Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska