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Indolium 1 for Advanced Melanoma Treatment
Application
A small molecule compound for the treatment of melanoma.
Key Benefits
Novel small molecule compound for the treatment of resistant melanoma.
Well tolerated in vivo.
Market Summary
Malignant melanoma is a type of skin cancer that begins in melanocyte cells. Melanoma is the 19th most commonly occurring cancer. Exposure to UV radiation...
Published: 11/20/2024
Contributor(s): Jack Arbiser
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Beta Blocker Isomers as Angiogenesis Inhibitors
Application
β-blocker inactive form of propranolol for treatment of angiogenic disease.
Key Benefits
Reduced side-effects, such as low blood pressure and low blood sugar.
Increased anti-angiogenic activity compared to the active isoform.
Market Summary
Angiogenesis is the growth of blood vessels from the existing vasculature. While it...
Published: 11/20/2024
Contributor(s): Jack Arbiser
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ItchyQuant: Numeric Scale for Itch
Application
Self-reported numeric rating scale for determining the severity of itch.
Key Benefits
Incorporates cartoons, making assessment easier to administer.
May determine severity of itchiness in pediatric population.
Market Summary
Itch (also known as pruritus) is an uncomfortable, irritating condition that involves any part of the body...
Published: 11/20/2024
Contributor(s): Suephy Chen
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Standard Dermatology Outcome Measures (SDOM) & SkinDexMini: Quality of Life Instruments for Skin Disease
Application
Questionnaires to measure quality of life and functional impact in patients with skin disease.
Key Benefits
A quantitative measure of disease burden in patients with skin disease.
SDOM can be used to measure a patient's response to a therapy.
SDOM may be useful as an end point for epidemiologic and burden of disease studies or...
Published: 9/26/2024
Contributor(s): Robert Swerlick, Suephy Chen, Mary-Margaret Chren
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Wound Care Booklet for Patient Use
ApplicationBooklet/card to help patients with low literacy care for wounds and track wound healing.Key BenefitsAvailable in English and Spanish.Includes pictures for patients with low literacy and low health literacy.Built in ruler and record space helps patients track wound size for easy reporting to clinician.Market SummaryWound care management is...
Published: 9/26/2024
Contributor(s): Georgette Cox
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Small Molecule NOX Inhibitors of Human Melanoma Cell Proliferation
Application
Triphenylmethane small molecules inhibiting NADPH oxidase (NOX) for the anti-proliferation of melanoma tumor cells.
Key Benefits
Modifies molecular interactions with cellular proteins, reducing cell tumor growth.
Compounds are capable of inhibiting cell proliferation to a greater extent than current competing NOX inhibitors for melanoma...
Published: 9/26/2024
Contributor(s): Jack Arbiser
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Scalpdex: A Quality of Life Instrument for Scalp Dermatitis
Application
A quantitative measure of disease burden in scalp dermatitis patients.
Scalpdex can be used to measure a patient's response to a therapy.
The instrument may be useful as a secondary or coprimary end point for clinical trials.
Technical Summary
Scalp dermatitis is predominantly caused by two common inflammatory dermatoses: psoriasis...
Published: 9/26/2024
Contributor(s): Suephy Chen, Jensen Yeung, Mary-Margaret Chren
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ItchyQol: A Pruritus-Specific Quality of Life Instrument
Application
A quantitative measure of disease burden in pruritus patients.
ItchyQol can be used to measure a patient's response to a therapy.
The instrument may be useful as a secondary or coprimary end point for clinical trials.
Technical Summary
Pruritus is the chief symptom in numerous dermatologic conditions, and a common symptom in...
Published: 11/20/2024
Contributor(s): Suephy Chen
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RosaQoL, a Rosacea-Specific Quality of Life Instrument
Application
A quantitative measure of disease burden in rosacea patients.
The instrument may be useful as a secondary or coprimary end point in addition to an objective severity rating by clinicians for clinical trials testing new therapies.
RosaQoL may be useful as an end point for epidemiologic and burden of disease studies.
Technical Summary
Rosacea...
Published: 9/26/2024
Contributor(s): Suephy Chen
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