Technology Listings


22 Results Sort By:
Real-Time RT-PCR Assay for SARS-CoV-2
Application Triplex, internally-controlled real-time RT-PCR for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Key Benefits Two viral targets to confirm detection in a single sample. Does not involve the performance of multiple reactions as are required for the majority of published assays. May be performed using several different...
Published: 4/8/2020       Inventor(s): Jesse Waggoner
Ebola Specific Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) Assay
ApplicationA cell based assay to quantify the titer of circulating Ebola glycoprotein (GP) antibodies that trigger antibody-dependent cell-mediated cytotoxicity (ADCC).Key BenefitsSpecific for detection of ADCC activity of Ebola virus antibodies or antisera.Applicable to all pathogenic strains of Ebola virus.Ebola GP-specific stable reporter cells eliminate...
Published: 11/26/2018       Inventor(s): Paul Spearman, Karnail Singh, Xuemin Chen
Assay to Measure Cell Traction Forces for High Throughput Drug Screening and Mechanical Phenotyping
ApplicationMechanically induced catalytic amplification reaction (MCR) as an assay for high throughput screening of drugs which target cellular mechanics and mechanical phenotyping of live cells.Key BenefitsAdaptable for high throughput screening of drugs that impair cell mechanics.Enables characterization of different cells types based on their traction...
Published: 6/26/2017       Inventor(s): Pui Yan Ma, Khalid Salaita
Tool for Measuring Cell Purity and Quality Control of Stem Cell-based Products
ApplicationCell-based assay for sensitive and specific detection of undifferentiated cells in stem cell-related research and development.Key BenefitsNanotechnology-based assay can detect residual undifferentiated cells and characterize cultures that may be tumorigenic. Technology is potentially more sensitive method compared to current methods. Market...
Published: 12/16/2016       Inventor(s): Chunhui Xu, Shuming Nie, Ximei Qian, Jingjia Han
Assay for Non-Nucleoside Inhibitors of the Measles and Nipah Viruses
Application A cell-based assay to screen for inhibitors of the measles virus (MV). Highly active compounds have been identified and analogs have been synthesized and evaluated. Key BenefitsPotent (sub-nM range), non-peptidic, non-nucleosidic compounds. Robust, cell-based, high-throughput screening assay. Technical Summary Vaccination serves as the only...
Published: 10/18/2016       Inventor(s): Richard Plemper, James Snyder, Aiming Sun
Quantitative ELISA for Determination of TrkB Activation
Application A quantitative enzyme-linked immunosorbent assay (ELISA) for monitoring endogenous rat tyrosine receptor kinase B (TrkB) activation. Key Benefits Two quantitative ELISA approaches provide reliable methods to quantify the intensity of TrkB receptor activation in primary neurons with endogenous TrkB receptor. Enables high-throughput drug...
Published: 4/27/2015       Inventor(s): Keqiang Ye
New Reagents for the Identification and Quantification of Most Pneumococcal Serotypes/Serogroups via Quantitative PCR
ApplicationPrimers and probes set for identifying and quantifying of individual Streptococcus pneumoniae (Sp) serotype/serogroup within a sample.Key Benefits Can identify and quantify 72 different Sp subtypes. Cryostable over a 2 year period. Sufficiently sensitive to identify very small copy numbers within a sample & to differentiate highly similar...
Published: 1/7/2015       Inventor(s): Jorge Vidal, Fuminori Sakai
Human PHF8 Protein
ApplicationHuman plant homeodomain finger protein 8 (PHF8) for use in assays to identify drugs that modulate human activity of the enzyme or to engineer recombinant protein for use in such assays. Key BenefitsAllows for the function of individual methyl marks to be identified. Applications towards mental retardation, cleft lip or palate, and other congenital...
Published: 1/14/2013       Inventor(s): Xiaodong Cheng, John Horton
Human KIAA1718 Protein Jumonji Domain
ApplicationEnzymatic domain of human KIAA1718 for use in assays to identify drugs that modulate enzyme activity or to engineer hybrid enzymes for use in such assays. Key BenefitsActs as a promiscuous enzyme. Applications towards mental retardation, cleft lip or palate, and other congenital abnormalities. Technical SummaryJumonji-C (JmjC) domain-containing...
Published: 1/14/2013       Inventor(s): Xiaodong Cheng, John Horton
Human PHF8 Protein Jumonji Domain
ApplicationEnzymatic domain of human plant homeodomain finger protein 8 (PHF8) for use in assays to identify drugs that modulate activity of the enzyme or to engineer hybrid enzymes for use in such assays.Key BenefitsActs as a promiscuous enzyme. Applications towards mental retardation, cleft lip or palate, and other congenital abnormalities. Technical...
Published: 1/14/2013       Inventor(s): Xiaodong Cheng, Justin Jones
1 2 3