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High-Throughput Platform for Imaging and Maintaining Cells in Culture
Application This closed-loop platform monitors and maintains traditional cell culture and bioengineered tissues to automate standard and custom cell maintenance protocols, including stem cell differentiations, bioengineered tissue generation, and functional maturation of complex cell cultures. Key Benefits Automation of cell culture maintenance Integration...
Published: 8/25/2021       Contributor(s): Vahid Serpooshan, Ayda Melika, Amir Pourmorteza
Multimodal Prospective Learning Test
Application Multimodal learning test to assess naming and facial recognition in post-operative epilepsy patients. Key Benefits Provides non-invasive, age-appropriate neuropsychological testing. Allows clinicians to simultaneously assess multiple modalities. Market Summary Epilepsy is a chronic neurological disorder characterized by unpredictable,...
Published: 12/10/2020       Contributor(s): Daniel Drane, Keith Adams
CRISPR Based System for Targeted Reduction of Gene Expression
ApplicationA CRISPR based gene silencing system using sequence specific RNA to repress expression of endogenous transcripts.Key BenefitsProvides a platform to target specific mRNA transcripts in both prokaryotic and eukaryotic cells. Potential therapeutic strategy against pathogenic bacteria and viruses. Market SummarySince the discovery of silencing...
Published: 12/10/2020       Contributor(s): David Weiss, Tim (Timothy) Sampson
Caspase-3 Deficient MEFs with Mutant Caspase-3 Re-Introduced
Application Mouse embryonic fibroblast (MEF) line deficient in caspase-3 that are reconstituted with constitutively expressed mutant versions of the protease. Key Benefits An immortalized caspase-3-deficient MEF cell line. Tool to study protease induced apoptosis. Technical Summary Emory inventors have discriminated a previously unknown role...
Published: 11/20/2020       Contributor(s): Lawrence Boise, Katelyn Ponder
tPAINT to Measure Molecular Forces in Live Cells
Application DNA-based probes to measure the nanoscale distribution of piconewton molecular forces in live cells. Key Benefits Provides maps of integrin tension with up to ˜25 nm resolution and piconewton force sensitivity for live-cell imaging. The tPAINT can be performed on a commercial TIRF microscope. Market Summary Emory inventors...
Published: 11/17/2020       Contributor(s): Joshua Brockman, Hanquan Su, Khalid Salaita
Additives that Increase Storage and Shelf Life of Platelets
Application Monoclonal antibody additive that inhibits ectodomain shedding of a platelet glycoprotein to improve platelet storage. Key Benefits Current storage techniques allows for limited storage times (5-7 days). New additive may enable platelet storage at 4°C, increase platelet storage time, and improve quality of stored platelets. Inhibits...
Published: 11/2/2020       Contributor(s): Renhao Li
Hemophilia-Related Distress Questionnaire
Application Instrument to quantitatively measure distress associated with hemophilia and its management. Key Benefits Concise, easy to score, and multi-factorial test. Consistent test-retest reliability. Promotes improved patient health outcomes. Market Summary In the US, approximately 400 babies per year are born with hemophilia and there...
Published: 10/19/2020       Contributor(s): Christine Kempton, Vaughn Barry, Shanna Mattis, Mary Lynch (O'Neill)
3D-Printed Mouse Headplates for Implantation of EEG, EMG and Depth Electrodes
Application Tool to precisely and reproducibly implant electrode and other instrumentation into the mouse brain for neurophysiology studies. Key Benefits Inexpensive, rapid and efficient reproduction of headplates. Allows consistent and quick surgical implantation. Capable of recording or stimulating multiple sites in the mouse brain. Market...
Published: 5/21/2020       Contributor(s): Nigel Pedersen, Lauren Aiani
Ribosome Pegging: An Antibiotic-free System to Produce Recombinant Proteins
Application Antibiotic-free method to prevent the growth of cells that fail to express high levels of a non-essential protein (target protein). Key Benefits Prevents the use of antibiotics and markers that promote resistance. Facilitates the deployment of recombinant bacteria in uncontrolled environments. Stabilizes heterologous expression of...
Published: 4/22/2020       Contributor(s): Ichiro Matsumura
C19Check: COVID-19 Severity Stratification Tool
Application Algorithm for screening of individuals exhibiting coronavirus disease (COVID-19) symptoms. Key Benefits Allows mass screening of potential COVID-19 patients. Alleviates burden on hospitals and doctors’ offices. Reduces unnecessary interactions with individuals. May be used in regions with low internet access. Market Summary Coronavirus...
Published: 4/8/2020       Contributor(s): Justin Schrager, Alexander Isakov, David Wright, Anna Yaffee, Arthur Kellermann
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