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Hemophilia-Related Distress Questionnaire
Application Instrument to quantitatively measure distress associated with hemophilia and its management. Key Benefits Concise, easy to score, and multi-factorial test. Consistent test-retest reliability. Promotes improved patient health outcomes. Market Summary In the US, approximately 400 babies per year are born with hemophilia and there...
Published: 10/19/2020       Inventor(s): Shanna Mattis, Mary Lynch (O'Neill)
3D-Printed Mouse Headplates for Implantation of EEG, EMG and Depth Electrodes
Application Tool to precisely and reproducibly implant electrode and other instrumentation into the mouse brain for neurophysiology studies. Key Benefits Inexpensive, rapid and efficient reproduction of headplates. Allows consistent and quick surgical implantation. Capable of recording or stimulating multiple sites in the mouse brain. Market...
Published: 5/21/2020       Inventor(s): Lauren Aiani
Ribosome Pegging: An Antibiotic-free System to Produce Recombinant Proteins
Application Antibiotic-free method to prevent the growth of cells that fail to express high levels of a non-essential protein (target protein). Key Benefits Prevents the use of antibiotics and markers that promote resistance. Facilitates the deployment of recombinant bacteria in uncontrolled environments. Stabilizes heterologous expression of...
Published: 4/22/2020       Inventor(s):  
Molecular Probe that Records Mechanical Information Produced by Living Cells
Application A molecular probe that stores and integrates short-lived cellular mechanical events over time. Key Benefits Quantitative method of measuring short-lived interactions between cells. Ideal for immunology-based assays Fluorescence-based and amenable as a drug screening research tool. Market Summary Studying the interplay between mechanical...
Published: 2/27/2020       Inventor(s): Khalid Salaita, Rong Ma
Platform for Transducing Target Cells with a Viral Vector
Application System for quickly and efficiently obtaining therapeutic levels of transduction. Key Benefits Uses less viral vector to achieve high gene transfer. Shortens transduction time. Produces clinically relevant gene modified cell numbers. Market Summary Information relay at the molecular level, such as the transcription of RNA into proteins,...
Published: 1/23/2020       Inventor(s): Reginald Tran, Wilbur Lam, Christopher Doering, H. (Harold) Trent Spencer
Reprogramming Human Urine Stem Cells into Vascular Tissue
Application System to generate vascular progenitor cells within naturally constructed (or formed) biomatrices from urine cells. Key Benefits Nearly limitless supply of source cells. Non-invasive method for harvesting source cells. Efficient endothelial cell generation with fewer steps and faster generation time than current standard for differentiating...
Published: 1/23/2020       Inventor(s): Young-Sup Yoon, Young-Doug Sohn, Sang-Ho Lee
Strategy to Identify miRNAs for Disease Diagnosis
Application Method to measure precursor and mature miRNA specifically. Key Benefits Unique primers can specifically identify miRNAs and precursor miRNAs by standard qRT-PCR without the requirement for an additional detection probe. Allows for amplification and quantification of both mature miRNA and precursor miRNAs. Potential technology to evaluate...
Published: 1/22/2020       Inventor(s): Wenming Li
Real-time, Particle-Tracking and Control Software for Electromagnetic Tweezers
Application Software to control electromagnetic tweezers and to track tethered particles in real-time in 3D. Key Benefits Electromagnets offer improved temporal response without mechanical vibration. 3D particle tracking utilizing a continuous LUT built from multidimensional spline fits of discrete data improves accuracy and provides precision...
Published: 1/14/2020       Inventor(s): Laura Finzi
Psychosis Prediction Using Speech Patterns
Application Linguistic software to predict and diagnose psychosis. Key Benefits New method of diagnosing psychosis. Very high accuracy rate (86.7%). Market Summary Psychotic disorders are mental illnesses characterized by delusions, hallucinations, and disorganized thinking and speaking. Schizophrenia is an example of a psychotic disorder....
Published: 1/14/2020       Inventor(s): Phillip Wolff, Jinho Choi
High-Resolution Field Inhomogeneity Correction for Magnetic Resonance Spectroscopy
Application Post-processing algorithm to correct field inhomogeneity in MR spectroscopy. Key Benefits Subvoxel field inhomogeneity correction enables CEST magnetic resonance imaging (MRI) Z-spectrum from body tissues where shimming is challenging. Intravoxel field inhomogeneity correction enables MR spectroscopy (MRS) and MR spectroscopy imaging...
Published: 1/13/2020       Inventor(s): Phillip Zhe Sun
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