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Predicting Treatment Response in Patients with Spinal Muscular Atrophy (SMA)
Application Prognostic model predicts treatment response to nusinersen (Spinraza®) in patients with spinal muscular atrophy. Key Benefits A prediction model using baseline CHOP-INTEND, IL-8, fractalkine, and MCP-1 accurately predicts CHOP-INTEND outcomes in children treated with nusinersen The model can also be incorporated into future therapeutic...
Published: 7/13/2021       Contributor(s):  
Vision Test for Non-Verbal Children
Application Vision testing for non-verbal children, the hearing impaired, and non English-speaking population. Key Benefits Simplifies vision testing for non-verbal children. Does not require any verbal communication to be used effectively. Technical Summary While traditional eye charts are often effective, they rely on verbal communication...
Published: 2/3/2021       Contributor(s): Amy Hutchinson, Caroline Cromelin, Cindy Harrington
Multiplex Serological Assays for SARS-CoV-2 Infection
Application Multiplex serological assays for SARS-CoV-2 infection with implications in diagnostics, vaccine responses, immunity, and prognosis. Key Benefits Can be used to identify patients who are at risk of severe disease early in infection. Can be used to assess immunity. Uses a comprehensive panel of antibodies to test with one sample. Market...
Published: 1/27/2021       Contributor(s): Frances Lee, John (Jack) Daiss, Natalie Haddad, Ignacio (Inaki) Sanz
Multimodal Prospective Learning Test
Application Multimodal learning test to assess naming and facial recognition in post-operative epilepsy patients. Key Benefits Provides non-invasive, age-appropriate neuropsychological testing. Allows clinicians to simultaneously assess multiple modalities. Market Summary Epilepsy is a chronic neurological disorder characterized by unpredictable,...
Published: 12/10/2020       Contributor(s): Daniel Drane, Keith Adams
3D Model for Analysis and Treatment Planning of Vascular Disease
Application A patient-specific, 3D model of pulmonary atresia for surgical planning. Key Benefits Patient-specific model. Allows for accurate surgical planning. Enables new anastomosis procedure. Market Summary Pulmonary atresia (PA), ventricular septal defect (VSD) with major aortopulmonary collateral arteries (MAPCAs) is a rare congenital...
Published: 12/8/2020       Contributor(s): Vahid Serpooshan, Holly Bauser-Heaton, Martin Tomov
Amino Acid-Derived Radiotracer Compounds for PET Cancer Imaging
Application New class of fluorine-18 labeled amino acid-derived radiotracer compounds for positron emission tomography (PET) cancer imaging. Key Benefits Next generation of cancer imaging agents. Enhanced sensitivity to detect glioblastoma, prostate cancer and other cancers. Market Summary PET imaging is a type of nuclear medicine procedure...
Published: 11/2/2020       Contributor(s): Mark Goodman, Lanny Liebeskind, Thomas Pickel
Targeted Theranostic NanoToxin for Treating Metastatic and Drug-resistant Tumors
Application Magnetic theranostic nano-toxin for imaging and drug delivery applications in cancer therapy. Key Benefits Induces tumor cell death via a different biological mechanism, compared to current chemotherapeutics, to overcome drug resistance mechanisms in tumor cells. Delivers high levels of therapeutic agents into metastatic tumors, while...
Published: 11/2/2020       Contributor(s): Lily Yang, Xiangxue Guo, Hui Mao, Wei Chen
Hemophilia-Related Distress Questionnaire
Application Instrument to quantitatively measure distress associated with hemophilia and its management. Key Benefits Concise, easy to score, and multi-factorial test. Consistent test-retest reliability. Promotes improved patient health outcomes. Market Summary In the US, approximately 400 babies per year are born with hemophilia and there...
Published: 10/19/2020       Contributor(s): Christine Kempton, Vaughn Barry, Shanna Mattis, Mary Lynch (O'Neill)
Targeted Theranostic NanoToxin for Treating Metastatic and Drug-resistant Tumors
Application Magnetic theranostic nano-toxin for imaging and drug delivery applications in cancer therapy. Key Benefits Induces tumor cell death via a different biological mechanism, compared to current chemotherapeutics, to overcome drug resistance mechanisms in tumor cells. Delivers high levels of therapeutic agents into metastatic tumors, while...
Published: 9/15/2020       Contributor(s): Lily Yang, Xiangxue Guo, Hui Mao, Wei Chen
Amino Acid-Derived Radiotracer Compounds for PET Cancer Imaging
Application A new class of fluorine-18 labeled amino acid-derived radiotracer compounds for positron emission tomography (PET) cancer imaging. Key Benefits Next generation of cancer imaging agents. Enhanced sensitivity to detect glioblastoma, prostate cancer and other cancers. Market Summary PET imaging is a type of nuclear medicine procedure...
Published: 6/29/2020       Contributor(s): Mark Goodman, Lanny Liebeskind, Thomas Pickel
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