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Mobile Phone Diagnostic for COVID-19
Application
Diagnostic and automatic surveillance to identify COVID-19 via smartphone in real-time.
Key Benefits
Provides real-time, rapid results.
Autonomous process.
Device does not require RNA isolation or amplification for viral detection.
Market Summary
Coronavirus (COVID-19) is an infectious disease that causes severe acute respiratory...
Published: 5/23/2023
Contributor(s): Khalid Salaita, Alisina Bazrafshan, Selma Piranej
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Blood-based Diagnostic Test for Anxiety
Application
A blood-based biomarker test for the diagnosis of anxiety disorders.
Key Benefits
Gene panel of at least seven biomarkers that may predict anxiety in humans.
Minimally invasive blood test.
May identify different forms of anxiety leading to personalized treatment and improved clinical outcomes.
Market Summary
Anxiety disorders are...
Published: 4/5/2023
Contributor(s): Reid Alisch, Pankaj Chopra
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Precursor PET Compound for Imaging Infections
Application
Diagnostic molecules for detecting bacterial infections using nuclear imaging.
Key Benefits
May improve the detection of infections within the body.
Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers.
Market Summary
The rising incidences of bacterial infections resistant...
Published: 4/5/2023
Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska
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Liquid-hydrogel Hybrid Microfluidic Device
Application
Measurement device for detecting of single-cell dynamics under environment perturbations or drug treatment.
Key Benefits
Fast determination of drug sensitivity.
Long-term continuous cell-fate tracking.
Time-lapse analysis of cell proliferation.
Cell community analysis: intra-species interactions, inter-species interactions.
Market...
Published: 4/5/2023
Contributor(s): Kyle Allison, Xin Fang, Devina Puri
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SARS-CoV-2 Neutralizing Human Monoclonal Antibodies
Application
Monoclonal antibodies to SARS-CoV2 for use in COVID-19 diagnostics and therapeutics.
Key Benefits
Demonstrably neutralizing, important for therapeutic mAbs.
Most bind both RBG and stalk portion of spike protein, useful in case SARS-CoV2 strains develop variation in RBD.
Market Summary
Coronavirus (COVID-19) is an infectious...
Published: 2/8/2023
Contributor(s): Jens Wrammert, Carl Davis, Mehul Suthar, Robert Kauffman
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A Predictive Marker and Treatment to Sensitize Multiple Myeloma Patients to Venetoclax (ABT-199)
Application
A marker that predicts Venetoclax (ABT-199) sensitivity that can also be targeted with a drug to help multiple myeloma patients.
Key Benefits
Marker that predicts if venetoclax will be an effective treatment in multiple myeloma patients.
A drug that targets venetoclax resistant multiple myeloma cells to improve treatment in patients.
Market...
Published: 5/8/2023
Contributor(s): Malathy (mala) Shanmugam, Richa Bajpai
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Serological Test for SARS-CoV-2
Application
Clinical assay for detecting SARS-CoV-2 neutralizing antibodies.
Key Benefits
Highly specific and sensitive.
Fewer false positives than commercially available tests.
Market Summary
SARS-CoV-2 is currently causing a devastating pandemic and there is a pressing need to understand the dynamics, specificity, and neutralizing...
Published: 5/4/2023
Contributor(s): Rafi Ahmed, Mehul Suthar, John Roback, Jens Wrammert, Robert Kauffman
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A New Method to Detect and Tackle Antibiotic Heteroresistance
Application
A method to detect heteroresistance to antibiotics in bacteria.
Key Benefits
Significantly faster than commercially available options.
Aside from the interferometer itself, no specialized reagents are required.
Inexpensive to use.
Market Summary
Antibiotic resistance is a significant threat to public health. Rapid and sensitive...
Published: 5/16/2023
Contributor(s): David Weiss, Peter Yunker, David Hufnagel, Arben (Ben) Kalziqi
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Software to Correct 4D CT Scan Image Distortion
Application
A software that employs unsupervised deep learning to correct 4D CT scan image distortion due to respiratory motions.
Key Benefits
Allows the generation of highly precise, motion-corrected 4D CT images
Market Summary
CT scans usually allow radiation oncologists to contour a tumor’s area and position. However, abdominal motions...
Published: 8/9/2022
Contributor(s): Yang Lei, Tian Liu, Xiaofeng Yang, Yabo Fu
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Low Dose PET/MRI and PET/CT Imaging
Application
A deep-learning based method for generating diagnostic-quality PET images from lower quality images to reduce scanning time and radiation exposure
Key Benefits
Generates a high quality synthetic high-count PET image from low-count PET image or CT scan image
Reduces radiation exposure to patient
Reduces scanning time
Market Summary
Positron...
Published: 8/9/2022
Contributor(s): Xiaofeng Yang, Yang Lei, Hui Mao, Tian Liu, Jonathon Nye, Xue (Xueyuan) Dong
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