|
Multi-Modal Sensing Platform for Diagnosing Depression and Schizophrenia
Application
A multi-sense deep learning platform and interview protocol used for detection and assessment of depression and schizophrenia.
Key Benefits
Automated and remote mental illness assessment without the need for self-reporting or clinical observation.
Improved disease tracking for patients and clinicians.
A more objective classifier and...
Published: 7/26/2024
Contributor(s): Gari Clifford, Robert Cotes, Mina Boazak, Zifan Jiang, Seyed Salman Seyedi, Ali Bahrami Rad
|
|
Smartphone Diagnostic for Rapid Respiratory Virus Detection
Application
Diagnostic and automatic surveillance platform to identify RSV, Influenza A, and COVID-19 in real-time.
Key Benefits
Rapid smartphone-based detection of multiple respiratory viruses in nasal swab, breath condensate, and saliva.
Requires few reagents and no expensive equipment.
Limit of detection on par with PCR and rapid readout.
Enables...
Published: 7/19/2024
Contributor(s): Selma Piranej, Khalid Salaita
|
|
Technology for Assessment in Enhancing Memory Measurement in ECT Therapy
Application
The Electroconvulsive Cognitive Assessment (ECA) is a 10-minute cognitive exam designed for use during and after Electroconvulsive Therapy (ECT). It focuses on assessing memory deficits associated with ECT, offering a quick and targeted evaluation tool for healthcare professionals.
Key Benefits
Rapid cognitive assessment in under 10...
Published: 4/23/2024
Contributor(s): Adriana Hermida
|
|
CXCR4-Targeting Molecules for Tumor Metastasis and PET Imaging
Application
Positron emission tomography (PET) imaging agents with high specificity for metastatic cancer.
Key Benefits
18F-labeled CXCR4 (partial) antagonist without stem cell mobilizing property is safe to be given to patient multiple times.
Identifies tumor location non-invasively and provides an indication of tumor’s metastatic potential.
Market...
Published: 4/23/2024
Contributor(s): Hyunsuk Shim, Mark Goodman, Dinesh Shetty, Yoon Hyeun Oum
|
|
Multimodal Identification of Atrial Fibrillation Recurrence Sites
Application
Identifies areas of interest associated with atrial fibrillation recurrences.
Key Benefits
Identifies sites associated with recurrences for AF patients.
Predict AF recurrence risk in patients’ post-catheter ablation.
Development of prediction model by extracting features from the surface of interest (SOI).
Market Summary
Atrial...
Published: 4/23/2024
Contributor(s): Abhishek Midya, Anant Madabhushi, Golnoush Asaeikheybari, Mina K. Chung, Amogh Hiremath, Moore Benjamin Shoemaker, Majd A. El-Harasis, John Barnard, Rod S. Passman
|
|
Markers Predictive of Therapeutic Response in B-cell Malignancies
Application
Test to detect NF-kB2 breaks to guide treatment with proteasome inhibitors and its use with other therapeutic agents.
Key Benefits
Improved the prediction model to determine which patients are more likely to respond to bortezomib treatment.
Improved the efficacy of treatment for patients with multiple myeloma and lymphomas.
Market...
Published: 5/21/2024
Contributor(s): Leon Bernal-Mizrachi
|
|
System for Assessing Health Severity and Predicting Readmissions
Application
A smartphone-based system for monitoring patients to identify and prevent severe cardiac events.
Key Benefits
A remote monitoring system that uses smartphone data to accurately predict a user’s risk for a severe cardiac event (e.g., heart attack).
Tracks the user's movement, location, and physical activity to calculate FDA-accepted...
Published: 7/26/2024
Contributor(s): Gari Clifford, Amit J. Shah, Ayse Cakmak, Erik Reinertsen
|
|
Combination Antibiotic Therapy to Exploit Multiple Heteroresistance
Application
Treatment with combinations of FDA-approved antibodies targeting small drug-resistant cell populations for infectious disease.
Key Benefits
Specific combinations of existing drugs that target small subpopulations of bacterial cells resistant to many standard of care treatment regimens.
Potential to overcome the drug resistance crisis...
Published: 7/26/2024
Contributor(s): David Weiss, David Hufnagel, Victor Band
|
|
Assays for Labeling and Evaluating Lysine Methylation
Application
A life science tool for evaluating protein lysine methylation for drug discovery and disease research.
Key Benefits
Highly specific labeling method for post-translational methylated lysine.
Potential to improve the understanding of protein lysine methylation and help develop new drugs to block its interactions across several disease...
Published: 6/21/2024
Contributor(s): Monika Raj, Ogonna Nwajiobi
|
|
Using Hetero-multivalent DNA-functionalized Materials to Detect Genetic Mutations
Application
Improving diagnostic accuracy using hetero-multivalent DNA-functionalized materials for disease targets containing one or more genetic mutations.
Key Benefits
Tunable oligos increase specificity and cooperative binding to the disease target of interest.
Distinguishes between cis- and trans mutations.
Identifies different strains of...
Published: 7/26/2024
Contributor(s): Brendan Deal, Khalid Salaita, Rong Ma, James Kindt
|