Technology Listings


Antibodies for Zika and Dengue Viruses

Applications
  • ELISA
  • Western Blot
  • Immunohistochemistry
Specificity
  • Human monoclonal
Technical Summary

Zika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion. The investigators have isolated and characterized monoclonal antibodies from patients infected with ZIKV that bind the ZIKV NS1 protein. Some of the mAbs display cross-reactivity with Dengue virus (DENV) NS1 and could potentially be used as filovirus detection antibodies or therapeutics.

Publication:

Zimmerman, M. G. et al. (2018). Cell Host Microbe., 24(5), pp. 731-742.

Patent Information
Tech ID: 18012
Published: 5/9/2019
Category
Diagnostics
Research Tools

Contact
Justin Burns
Assistant Director, Licensing
Emory University
404-727-4968
justin.burns@emory.edu

Inventor(s)
Jens Wrammert
Mark Mulligan

Keywords
Antibody
Microbiology/Infectious Diseases