2 Results

Sort by: Published date Updated Date Title ID Descending Ascending

Derivatives as CXCR4 Modulators for the Treatment of Inflammation and Metastasis Application Amide derivatives as chemokine receptor type 4 (CXCR4) modulators for the treatment of inflammation or prevention of cancer cell metastasis. Key Benefits Excellent binding affinity, compared to currently available compounds targeting CXCR4 receptor. Stability in plasma compared to protein/peptide agonists of CXCR4, these amide derivatives... Published: 4/23/2024       Contributor(s): Hyunsuk Shim, Renren Bai, Qi Shi

CXCR4 Modulator for Preventing Cancer Metastasis Application Amine derivatives as chemokine receptor type 4 (CXCR4) modulators to treat breast cancer and block tumor metastasis. Key Benefits New class of anti-cancer drugs targeting CXCR4 instead of COX pathway. Partial antagonists are safer for use because they do not mobilize stem cells. Market Summary CXC chemokine receptor 4 (CXCR4) and... Published: 4/23/2024       Contributor(s): Hyunsuk Shim, Renren Bai, Suazette Mooring