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CXCR4 Antagonists for the Treatment of Cancer
Application Small molecules containing either the piperidine or piperazine core which act as antagonists to C-X-C chemokine receptor type 4 (CXCR4) and may be orally administered. Key Benefits Orally administered CXCR4 antagonists with diverse clinical applications in oncology. Mobilize white blood cells in mice in a dose-dependent manner. Cause...
Published: 4/23/2024       Contributor(s): Lawrence (larry) Wilson, Dennis Liotta, John Wiseman, Michael Natchus