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Improved Clinical Diagnostic Method for SARS-CoV-2 Infection
Application
A more reliable and accurate method for diagnosing SARS-CoV-2 infection based on the biochemical interactions between the spike trimer and ACE-2 protein.
Key Benefits
A fast, affordable, and easy-to-use SARS-Cov-2 diagnostic test for use in clinical settings.
Market Summary
SARS-CoV-2 has evolved significantly since the onset of...
Published: 11/27/2023
Contributor(s): John Roback, Andrew Neish, Narayanaiah Cheedarla, Hans Verkerke, Huixia Wu, William Osick, Kaleb Mclendon, Sindhu Potlapalli
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Serological Test for SARS-CoV-2
Application
Clinical assay for detecting SARS-CoV-2 neutralizing antibodies.
Key Benefits
Highly specific and sensitive.
Fewer false positives than commercially available tests.
Market Summary
SARS-CoV-2 is currently causing a devastating pandemic and there is a pressing need to understand the dynamics, specificity, and neutralizing...
Published: 12/20/2023
Contributor(s): Rafi Ahmed, Mehul Suthar, John Roback, Jens Wrammert, Robert Kauffman
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Algorithm and Software Application for the Diagnosis of Adverse Reactions to Blood Transfusion
Application
Web-based and mobile application based on the National Healthcare Safety Network’s Biovigilance Component Hemovigilance Module Surveillance Protocol to aid in the identification of adverse reactions to transfusions easily and accurately.
Key Benefits
Provides a quick, easy, and accurate method to identify transfusion reactions...
Published: 4/24/2024
Contributor(s): John Roback, Geoffrey Smith
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Biologic Therapeutic for Graft-versus-Host Disease (GvHD)
Application
Biotherapeutic activation of toll-like receptor 5 (TLR5) to treat graft-versus-host disease (GvHD).
Key Benefits
Administration of flagellin reduces both acute and chronic GvHD.
Contrary to immunosuppressive drugs, flagellin enhances immunity and protects patients from opportunistic infections.
Market Summary
Transplant recipients...
Published: 4/23/2024
Contributor(s): Mohammad Hossain, Andrew Gewirtz, John Roback, Edmund Waller
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Evaluation of Red Blood Cells (RBC) to Predict Post-Transfusion Survival
Application
Technique to evaluate red blood cell units (RBC) and predict their post-transfusion survival.
Key Benefits
No existing techniques to predict post-transfusion survival of RBC units.
Provides a quality control technique to predict post-transfusion survival of RBC units prior to transfusion.
Market Summary
Millions of patients are...
Published: 4/23/2024
Contributor(s): James Zimring, John Roback, Larry Dumont
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