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The Antitussive Drug Noscapine & its Derivatives as Anti-Tumor Agents
ApplicationCan be used for the treatment of neoplastic disease.SummaryA variety of chemotherapeutic agents interact with tubulin, the major protein of mitotic spindles, resulting in mitotic arrest and ultimately cell death in rapidly dividing cells. Athough tubulin-targeting agents are capable of arresting cells in mitotis, these drugs indiscrimina...
Published: 6/6/2013       Inventor(s): Harish Joshi, Judith Kapp, Yong Ke, Fuqiang Liu, Keqiang Ye, Jaren Landen, David Archer, Cheryl Armstrong