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Synthetic Analogues of Progesterone
Application Therapeutic treatment of traumatic brain injury and other uses of progesterone where composition of matter intellectual property are required. Key Benefits 20 fold increase in solubility relative to the hormone progesterone. Synthetic analogues are as effective as progesterone in reducing cerebral edema following traumatic brain injury....
Published: 4/23/2024       Contributor(s): Dennis Liotta, Christopher Macnevin, Donald Stein, Michael Natchus, David Guthrie, Mark Lockwood, Iqbal Sayeed
Progesterone Shows Promise in Treating CNS Tumors
ApplicationTreatment for neuroblastoma and other tumors in the central nervous system.Key BenefitsInduces cell death in tumor cells while having no negative effects on surrounding neurons. Slows the rate of neuroblastoma tumor growth. Technical SummaryEmory researchers have shown that progesterone caused significant cell death in tumor cells while remaining...
Published: 4/23/2024       Contributor(s): Donald Stein, Iqbal Sayeed, Fahim Atif