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Targetin: New Targeted Non-Toxic Anti-Cancer Drug
Application Compositions and methods for treating cancer and inflammatory disease using noscapine and noscapine analogues conjugated to targeting molecules. Key Benefits Noscapine is a plant-derived alkaloid with a long-history of human use as an anti-cough agent. Noscapine is currently in phase I clinical trials for the treatment...
Published: 4/23/2024       Contributor(s): Harish Joshi, Suryan Vangapandu, Ritu Aneja
Synthesizing Noscapine Analogues for Drug Resistance
Application Synthesis of noscapine analogs and their use as cancer treatments, including drug resistant cancers. Key BenefitsEfficient, high yielding synthesis of noscapine derivatives. Selective for cancer cells over normal human cells.Technical Summary The effectiveness of microtubule-targeting drugs as treatments for cancer has been validated through...
Published: 4/23/2024       Contributor(s): Harish Joshi, Ritu Aneja