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Brominated Noscapine as a Potent Anti-Inflammatory Key Benefits Noscapine has been used safely in humans for over 30 years. Noscapine analogs can inhibit inflammation in in vitro models. Technical Summary The innate immune system plays a crucial role in host defense and homeostasis. Innate immune responses are induced when pattern recognition receptors such as Toll-like receptors (TLR) sense... Published: 4/23/2024       Contributor(s): Susu Zughaier, Ritu Aneja, David Stephens

Novel Genetic Element Identified for Macrolide Resistance in Pneumococcal Infections Application Genetic element that confers macrolide drug resistance in Streptococcus pneumoniae for use in patient screening and diagnosis as well as drug development. Key Benefits Genetic element allows identification of Streptococcus pneumoniae strains that are resistant to macrolide antibiotics. Expressed efflux proteins identified by this... Published: 4/23/2024       Contributor(s): David Stephens, Kathryn Gay