The Antitussive Drug Noscapine & its Derivatives as Anti-Tumor Agents
Can be used for the treatment of neoplastic disease.
A variety of chemotherapeutic agents interact with tubulin, the major protein of mitotic spindles, resulting in mitotic arrest and ultimately cell death in rapidly dividing cells. Athough tubulin-targeting agents are capable of arresting cells in mitotis, these drugs indiscrim...
Inventor(s): Harish Joshi, Judith Kapp, Yong Ke, Fuqiang Liu, Keqiang Ye, Jaren Landen, David Archer, Cheryl Armstrong