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The Antitussive Drug Noscapine & its Derivatives as Anti-Tumor Agents
Application Can be used for the treatment of neoplastic disease. Summary A variety of chemotherapeutic agents interact with tubulin, the major protein of mitotic spindles, resulting in mitotic arrest and ultimately cell death in rapidly dividing cells. Athough tubulin-targeting agents are capable of arresting cells in mitotis, these drugs indiscrim...
Published: 6/6/2013       Inventor(s): Harish Joshi, Judith Kapp, Yong Ke, Fuqiang Liu, Keqiang Ye, Jaren Landen, David Archer, Cheryl Armstrong