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Ebola Specific Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) Assay
ApplicationA cell based assay to quantify the titer of circulating Ebola glycoprotein (GP) antibodies that trigger antibody-dependent cell-mediated cytotoxicity (ADCC).Key BenefitsSpecific for detection of ADCC activity of Ebola virus antibodies or antisera.Applicable to all pathogenic strains of Ebola virus.Ebola GP-specific stable reporter cells ...
Published: 11/26/2018       Inventor(s): Paul Spearman, Karnail Singh, Xuemin Chen
EasyOocyte: Software for Recording Digital Record from Xenopus Laevis Oocytes
ApplicationSoftware to automate drug application and data collection for recording from Xenopus oocytes.Key BenefitsEnables automation of pharmacological experiments.Improves the efficiency of research and pharmaceutical drug development.Technical SummaryEmory University researchers have developed software to increase the efficiency of electrophysi...
Published: 10/16/2018       Inventor(s): Stephen Traynelis, Kevin Ogden
Respiratory Syncytial Virus Strain A2-2-20F
ApplicationStrain of respiratory syncytial virus (RSV) for vaccine and therapeutic research and development.Key BenefitsHigher early viral load.Induces greater necrotic airway damage and neurophil infiltration.Market SummaryRSV is a highly contagious and ubiquitous virus that causes respiratory tract infections in individuals of all ages, particula...
Published: 10/16/2018       Inventor(s): Martin Moore
INFORMED: Instant Functional Outcomes Report for Meaningful Encounters in Dialysis
ApplicationSoftware report that records and displays the domains of physical functioning for dialysis patients to inform clinicians' shared decision making.Key BenefitsEnables longitudinal tracking of patient information on functioning over time.Displays information across multiple domains of physical functioning.Increases cooperation of patient wi...
Published: 10/2/2018       Inventor(s): Laura Plantinga, Brian Jones, Anna Vandenberg, Leigh Nadel
Knock-In Mouse Model of Oculopharyngeal Muscular Dystrophy
ApplicationConditional knock-in mouse mimicking Oculopharyngeal muscular dystrophy.Technical SummaryOculopharyngeal muscular dystrophy (OPMD) is rare genetic disease caused by a mutation in the PABPN1 gene. In this mutation, the number of GCG trinucleotide repeats at the 5' end of PABPN1 are increased, which leads to an expansion of an alanine repe...
Published: 9/27/2018       Inventor(s): Grace Pavlath, Anita Corbett, Katherine Vest
Human Osteopontin Knock-in Mouse Line
ApplicationMouse lines expressing isoforms a, b, and c of the Human Osteopontin (OPN) protein for cancer research.Technical SummaryThe murine OPN is not subject to splicing and therefore does not express different isoforms. Human cancers express splice variants. Emory researchers developed these mouse models to express each isoform independently fr...
Published: 9/26/2018       Inventor(s): Alicia Lyle
3q29 Deletion Mice
ApplicationMouse models with the deletion of 3q29 for the study of neurological disorders such as schizophrenia, autism, and anxiety disorders.Technical SummaryCopy Number Variants (CNV’s) are large genomic deletion or duplications. One of the CNV’s, the 3q29 deletion, confers more than 40 fold increase in risk of schizophrenia. Most pe...
Published: 8/23/2018       Inventor(s): Tamara Caspary, David Weinshenker, Stephen Warren
Cre-Lox PAR1 Conditional Knockout Mouse
Key BenefitsTissue-specific knockout mouse, allowing PAR1 to be inactivated in specific cell types in certain tissue.Inducible knockout mouse, allowing PAR1 to be temporally suppressed at a given time-point in embryonic, post-natal or adult animals.Eliminates drawbacks and side effects of traditional knockout processes that eliminate genes from the...
Published: 6/26/2018       Inventor(s): Stephen Traynelis
Specialized Cell Culturing Media for Enhanced Antibody Secretion and Plasma Cell Survival
ApplicationCell culture media that promotes the survival of human plasma cells and enables immunoglobin (Ig) secretion from such plasma cells.Key BenefitsFacilitates the isolation of antibody-secreting cells (ASCs) found in blood after antigen exposure, which can be used to identify an active antigen or pathogen causing illness.Composed of factors ...
Published: 5/24/2018       Inventor(s): Frances Lee, Ignacio (Inaki) Sanz, Doan Nguyen
Wound Care Booklet for Patient Use
ApplicationBooklet/card to help patients with low literacy care for wounds and track wound healing.Key BenefitsAvailable in English and Spanish.Includes pictures for patients with low literacy and low health literacy.Built in ruler and record space helps patients track wound size for easy reporting to clinician.Market SummaryWound care management i...
Published: 4/9/2018       Inventor(s): Georgette Cox
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