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ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to stud...
Published: 7/9/2019       Inventor(s): Erwin Van Meir
ADGRB1/BAI1 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B1, brain-specific angiogenesis inhibitor-1 (ADGRB1/BAI1) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB1/BAI1 gene. These mice were developed through homologous recombination and have LacZ gene knock-in. Mice were...
Published: 7/9/2019       Inventor(s): Erwin Van Meir
Parent-Rated Anxiety Scale for Autism Spectrum Disorder (PRAS-ASD)
ApplicationScale/survey instrument for measuring anxiety in children with autism based upon a parent report.Key BenefitsIncludes 25-item measure for anxiety.Tested in a large-scale survey and clinical setting.Market SummaryAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication deficits and repetitive b...
Published: 7/8/2019       Inventor(s): Lawrence Scahill, Luc Lecavalier, Michael Aman, Karen Bearss
ItchyQuant: Numeric Scale for Itch
ApplicationSelf-reported numeric rating scale for determining the severity of itch.Key BenefitsIncorporates cartoons, making assessment easier to administer.May determine severity of itchiness in pediatric population.Market SummaryItch (also known as pruritus) is an uncomfortable, irritating condition that involves any part of the body and creates ...
Published: 6/3/2019       Inventor(s): Suephy Chen
Antibodies for Zika and Dengue Viruses
ApplicationsELISAWestern BlotImmunohistochemistrySpecificityHuman monoclonalTechnical SummaryZika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion. The investig...
Published: 5/9/2019       Inventor(s): Jens Wrammert, Mark Mulligan
Study Management and Retention Toolkit (SMART)
ApplicationMobile app and desktop application for management of research studies involving human patients.Key BenefitsSupports a variety of study formats.Combines management of all parts of study in one place.Automatically reminds patients and research staff of upcoming appointments and tasks.Improves communication between study admin and study par...
Published: 5/8/2019       Inventor(s): Eli Rosenberg, Patrick Sullivan
Non-Invasive Millimeter Depth Near-Infrared Monitoring System
ApplicationFrequency domain near-infrared spectroscopy (fdNIRS) system for non-invasive characterization of blood volume and tissue oxygen saturation at millimeter-scale depths.Key BenefitsNoninvasive optical method for monitoring tissue oxygen level and blood volume for brain research in small animals.Provides portable, cost-effective alternative ...
Published: 4/12/2019       Inventor(s): Erin Buckley, Seung Yup Lee
Standard Dermatology Outcome Measures (SDOM) & SkinDexMini: Quality of Life Instruments for Skin Disease
ApplicationQuestionnaires to measure quality of life and functional impact in patients with skin disease.Key BenefitsA quantitative measure of disease burden in patients with skin disease.SDOM can be used to measure a patient's response to a therapy.SDOM may be useful as an end point for epidemiologic and burden of disease studies or clinical trial...
Published: 3/29/2019       Inventor(s): Robert Swerlick, Suephy Chen, Mary-Margaret Chren
Adherence to Refills and Medications Scale (ARMS)
ApplicationQuestionnaire to assess self-reported adherence to medication for patients of all literacy levels.Key BenefitsIncreases patient adherence to medication prescription.ARMS-D (diabetes-specific) identifies barriers to adherence.Market SummaryTaking medication on time is crucial for the successful management of chronic illness, but only 50%-...
Published: 1/23/2019       Inventor(s): Sunil Kripalani, Terry Jacobson
IFN╬│ Prelicensing for Improved Mesenchymal Stromal Cell Function Post-Thaw
ApplicationMesenchymal stromal cells (MSC) prelicensed with pro-inflammatory cytokines for improved survival and immunosuppressive properties following cryopreservation.Key BenefitsPreserves the immunosuppressive function of MSCs following thawing.Improves effectiveness of transplanted MSCs following cryopreservation.Market SummaryMesenchymal strom...
Published: 1/22/2019       Inventor(s): Jacques Galipeau, Raghavan Chinnadurai
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