Technology Listings

cDNA and Cell Line for L-Proline Transporter


Cloning and studying the L-proline transporter.

Technical Summary

This invention is the first cDNA clone encoding a L-proline transporter. The clone makes it possible to perform high-level structural analysis of L-proline uptake. The clone permits the generation of antibodies capable of specifically recognizing L-proline in the pathways in which it is expressed. The precise role of L-proline as a neurotransmitter is the subject of current investigation. Certain results suggest that L-proline plays a role in interacting with glutamatenergic neurons, possibly as an inhibitor. In the short term, the cDNA should prove a valuable tool in elucidating the role of L-proline. As the role of L-proline is better defined, therapeutic applications for the cDNA are likely to emerge.

Patent Information
App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Utility(parent) United States 07/879,617 5,580,775 5/1/1992 12/3/1996 12/3/2013
Tech ID: 92027
Published: 2/24/2009
Research Tools

Hyeon (Sean) Kim
Licensing Associate
Emory University

Randy Blakely
Marcia Caron
Robert Fremeau

Cell Line