Technology Listings

S1112 Anti-SG2NA Monoclonal Antibody

  • Immunoprecipitation
  • Immunofluorescence

Human, mouse, and rat S/G2 nuclear autoantigen (SG2NA) protein


Mouse monoclonal

Technical Summary

S/G2 nuclear autoantigen (SG2NA) is a protein of the striatin family expressed in most cells that act as a scaffold to organize a large signaling complex containing kinases, protein phosphatase 2A, and other proteins. It forms heteromers with other striatin-family members (striatin and zinedin) and may be regulated by Ca(2+) given that it has a calmodulin binding domain. The antibody is directed against a peptide from the protein located in the 1st third of the protein. It is capable of immunoprecipitation as well as co-immunoprecipitation with other proteins associated with SG2NA, such as Mob3/phocein and proteinphosphatase 2A. Although not yet tested, it may work in other applications as well. Early experiments suggest that it also works in immunofluorescence. The hybridoma provides a continuous source of monoclonal antibody that will help provide consistency of results and can be used in multiple applications.

Patent Information
Tech ID: 12132
Published: 9/24/2012
Research Tools

Rajsekhar Guddneppanavar
Licensing Associate
Emory University

David Pallas