- Western Blot
- Immunohistochemistry (Paraffin)
GST-tagged recombinant protein corresponding to the N-terminus sequence of rat Ca(v) 1.3 alpha1 subunit.
Ca(v) 1.3 alpha1 subunit is a part of the Ca(v) 1.3 voltage-gated Ca2+ channel, which has become of key importance in regulating Ca2+ at excitatory synapses. The Ca(v) 1.3 channel controls neurotransmitter release from inner hair cells, release of insulin in the pancreas and pace-making activity in the heart. The Ca(v) 1.3 alpha1 subunit interacts with PDZ and is thought to regulate the activity of the Ca(v) 1.3 channel.
Publication: Calin-Jageman I, et al. (2007).J Neurosci. 27:1374-1385.