Technology Listings


Rabbit Polyclonal Cav1.3 Antibodies

Applications
  • Western Blot
  • Immunohistochemistry (Paraffin)
Specificity
  • Human
  • Rat
Subtype

Polyclonal

Immunogen

GST-tagged recombinant protein corresponding to the N-terminus sequence of rat Ca(v) 1.3 alpha1 subunit.

Technical Summary

Ca(v) 1.3 alpha1 subunit is a part of the Ca(v) 1.3 voltage-gated Ca2+ channel, which has become of key importance in regulating Ca2+ at excitatory synapses. The Ca(v) 1.3 channel controls neurotransmitter release from inner hair cells, release of insulin in the pancreas and pace-making activity in the heart. The Ca(v) 1.3 alpha1 subunit interacts with PDZ and is thought to regulate the activity of the Ca(v) 1.3 channel.

Publication: Calin-Jageman I, et al. (2007).J Neurosci. 27:1374-1385.

Patent Information
Tech ID: 10002
Published: 9/30/2011
Category
Research Tools

Contact
Rajsekhar Guddneppanavar
Licensing Associate
Emory University
RGUDDNE@emory.edu

Inventor(s)
Amy Lee

Keywords
Antibody