Monoclonal and polyclonal antibodies that recognize the PP2A A subunit
The inventor has made monoclonal (4G7) and polyclonal (R39) antibodies to the PP2A A subunit peptide (DP32). Most A subunit antibodies available are polyclonal antibodies. This hybridoma provides a continuous source of monoclonal antibody that will help provide consistency of results better than with polyclonal antibodies. May be useful for detecting A alpha or A beta mutants or expression changes that may contribute to cancer or Alzheimer's Disease risk. Mutations in the A subunit may also be able to be detected in cancer in part through using this antibody.