- Software tracks and sorts genetic information among animals for
transplantation and vaccine studies.
- Pedigree analysis for animal breeders.
- Allows for easy visualization, searching and matching of genetic
information such as MHC type.
- Simplifies the process of setting up animal matings.
- Built on open source software, allowing the user to custom tailor it to
Researchers at Emory University have developed a software program that
simplifies monitoring and tracking of an animal's genetic background. Knowledge
of genetic background is of particular importance in non-human primate
transplant and vaccine studies. A major challenge with transplantation studies
is transplant rejection due to differences in major histocompatibility (MHC)
types between animals. If the donor and recipient are of different subtypes, the
transplant will be recognized as non-self and an immune response will be
mounted. As most primates only produce one offspring every 18 months, proper MHC
matching and tracking are crucial for every experiment. This technology
simplifies the process of MHC compatibility matching. With vaccine studies,
different MHC types and polymorphisms can alter susceptibility to viruses and
response to vaccines. Therefore, it is crucial to accurately document the MHC
types of animals in these studies and the relationships between animals. Beyond
MHC information, this software could be used to track any number of genetic
traits within a population of animals, making this software of particular
utility to animal breeders. Whether the purpose is to increase or decrease
genetic diversity in a population of animals, this software simplifies the
process of tracking genetic traits and familial relationships for researchers
Software has been designed, copyrighted, and trademarked.