A system to predict the onset of seizures associated with epilepsy and abort such seizure activity.
Epilepsy affects approximately 1% of the population in the United States and approximately 2% of the population worldwide. Of those affected by the disease, approximately one-third have seizures that cannot be controlled by medication or cured by surgery. Epilepsy surgery requires locating the region of the brain where seizure onset occurs and the pathways through which the seizures spread, a process that is not completely accurate and reliable. Moreover, epilepsy surgery is accompanied by the inherent risk of neurologic injury, disfigurement and other complications. Some individuals have epileptic seizures that cannot be controlled by standard medication, are inoperable because seizure onset is not localized, or originate from vital areas of the brain which cannot be surgically removed. These individuals may resort to high doses of intoxicating medications and/or other experimental therapies.
Dr. Brian Litt and his colleagues have developed a system to predict the onset of epileptic seizures. The technology can predict the onset of a seizure with such accuracy that the activity of the brain can be monitored by an implantable device to warn a patient of the likelihood of an impending seizure. A patient and/or physician can take preventative actions through application of intervention measures to abort or modulate the seizure prior to clinical onset.