Technology Listings


Human Stool Specimens with Quantitatively Titered Norwalk Viruses

Applications

Human stool samples with pre-determined Norwalk virus titer that could be used as positive controls for Norwalk Virus-related studies or tests.

Key Benefits
  • Virus titer in each specimen has been pre-determined quantitatively.
  • Accurate positive controls for disinfection studies as well as water/food quality control examinations.
Technical Summary

Norwalk viruses (NVs), also known as noroviruses, are the most common cause for viral gastroenteritis (stomach flu) in humans. According to CDC?s latest report, the viruses contribute to ~21 million cases of acute gastroenteritis each year including ~70,000 hospitalizations and 800 deaths.

Unlike other microorganisms, NVs cannot be cultured in the lab, and stools from infected humans are the only source of infectious noroviruses. In order to simplify the testing procedure for NVs, researchers at Emory generated stool specimens by challenging healthy adults with a known dose of safety-tested Norwalk virus inoculum. In this case, each collected sample has well-characterized infecting strain, and the viral titer has been quantitatively determined via RT-qPCR.

Developmental Stage

Samples in stock.

Patent Information
Tech ID: 12175
Published: 1/8/2013
Category
Research Tools

Contact
Cale Lennon
Director, Licensing
Emory University
404-712-4758
jlennon@emory.edu

Inventor(s)
Christine Moe
Juan Leon

Keywords
Gastroenterology
Microbiology/Infectious Diseases