Technology Listings


DNA Methyltransferase Dnmt3a Antibody

Applications
  • Immunoblotting
  • Immunoprecipitation
  • Western Blot
Specificity

Mouse and human Dnmt3a - Specifically K44me2 of mDnmt3a and K47me2 of hDNMT3A

Subtype

Rabbit Polyclonal

Technical Summary

MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. DNA methylation and H3K9 methylation appear to co-occur in chromatin. The antibody was raised against the peptide CSATAR(Kme2)VGRPGR for mouse and YEPSTTAR(Kme2)VGRPGR for human. The peptide was conjugated to KLH via the N-terminal cysteine.

Publication: Chang, Y et al. Nat Commun, 2011. 2: 533.

Patent Information
Tech ID: 12016
Published: 7/6/2012
Category
Research Tools

Contact
Rajsekhar Guddneppanavar
Licensing Associate
Emory University
RGUDDNE@emory.edu

Inventor(s)
Xiaodong Cheng
Xing Zhang

Keywords
Antibody