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Plasmids for Expression of the Catalytic Domain of PRDM9 Application Plasmids to produce the catalytic domain of human PRDM9 or mouse Prdm9 protein, a robust methyltransferase generating trimethylation of histone H3 lysine 4 (H3K4me3). Technical Summary PRDM9 specifically trimethylates lysine 4 of histone H3, but does not have the ability to mono- and dimethylate lysine 4 of histone H3. H3K4 methylation... Published: 4/23/2024       Contributor(s): Anamika Patel, Xiaodong Cheng

Chemically Induced Pluripotent Stem (CiPS) Cells Application Generation of pluripotent stem cells from adult somatic cells for medical use. Key Benefits No exogenous genetic manipulations, which minimize oncogenic effects, were observed in current methods. Peripheral blood can be used as a source of parent cell instead of fibroblasts or keratinocytes. Market Summary The economic and psychological... Published: 4/23/2024       Contributor(s): Young-Sup Yoon, Ji Woong (Jay) Han, Xiaodong Cheng, Antonello Mai