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Mouse Systems for Evaluating Antiviral Agent Toxicity
Application
Transgenic mice with myocardial targeted overexpression of genes encoding proteins for mitochondrial import, phosphorylation, dephosphorylation, and mitochondrial DNA replication.
Key Benefits
Unique in vivo method to elucidate mechanism of AIDS related mitochondrial cardiomyopathy.
Selective overexpression of both native and mutant...
Published: 11/6/2023
Contributor(s): William Lewis, William Copeland
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