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Polydimethylsiloxane (PDMS) as a Replacement Substrate for Live Cell Imaging and UV Microscopy
­ Application Visualize cells and tissues utilizing UV microscopy. Key Benefits Low cost. Quick diagnostic for blood cultures especially for cancer diagnosis or Sickle cell anemia. Ability to visualize live cells and tissues via UV microscopy. Label and fixative free. Market Summary Polydimethylsiloxane (PDMS) is a silicon-based organic...
Published: 3/19/2024       Contributor(s): Evelyn Kendall Williams, Wilbur Lam, Ashkan Ojaghi, Francisco Robles
Platform for Transducing Target Cells with a Viral Vector
Application System for quickly and efficiently obtaining therapeutic levels of transduction. Key Benefits Uses less viral vector to achieve high gene transfer. Shortens transduction time. Produces clinically relevant gene modified cell numbers. Market Summary Information relay at the molecular level, such as the transcription of RNA into proteins,...
Published: 12/1/2023       Contributor(s): Reginald Tran, Wilbur Lam, Christopher Doering, H. (Harold) Trent Spencer
Mobile Application for Remote Screening of Abdominal Pain
ApplicationMobile application and program to remotely identify and assess severity of tenderness and abdominal pain.Key BenefitsAllows physician to replicate physical abdominal exam remotely.Eliminates distance barrier, increasing access to medical service.Potentially reduces need for in-person visits and costs.Market SummaryAbdominal (or stomach) pains...
Published: 7/28/2023       Contributor(s): Alexander Weiss, David Myers, Wilbur Lam
Micron-Sized Drug Vehicle for Unregulated Blood Clotting
Application Fibrinogen-coated micron-sized drug vehicles for targeted treatment of unregulated blood clotting. Key Benefits Facilitates targeted release of drugs specifically for blood clotting disorders. Drug delivery vehicle can be used with newly discovered or known therapeutics on the market. Site specific biological mechanism may help increase...
Published: 3/1/2024       Contributor(s): Caroline Hansen, Yumiko Sakurai, Wilbur Lam, Andrew Lyon
Microfluidic Device for Increased Viral Transduction Efficiency
Application Microfluidic chip device for facilitating high throughput viral transduction for gene therapy applications. Key Benefits Improves surface-to-volume ratio, allowing more efficient contact between lentiviruses and cells Increases efficiency while maintaining cell viability of traditional methods. Enables gene transfer for non-adherent...
Published: 1/10/2024       Contributor(s): Reginald Tran, Wilbur Lam, David Myers, Christopher Doering, H. (Harold) Trent Spencer
Microfluidic Device Enhances Understanding of Clot Formation
Application A microfluidic device for the measurement and quantification of the mechanical forces that occur during clot formation for use in hematology research or for diagnostic purposes. Key Benefits Is capable of measuring platelet-platelet interactions at the single cell level that is not possible with current tools. Facilitates quick &...
Published: 11/6/2023       Contributor(s): David Myers, Wilbur Lam, Yongzhi Qiu
Microfluidic Device for Delivery of Therapeutics into Cells
Application Microfluidic slide with individual cell holders for use in microinjection procedures. Key Benefits Open system - compatible with other microinjection technologies and existing research instrumentation. Compatible with both adherent and non-adherent cells. Enables high-throughput and high-precision delivery of substances into cells,...
Published: 7/28/2023       Contributor(s): Wilbur Lam, David Myers, Zhengchun Peng, Gang Bao