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CXCR4 Antagonists in Treatment of Cancer
Application
Nonpeptidic molecules that block the chemokine receptor, CXCR4, for treatment of proliferative disorders including inhibition of cancer metastasis.
Key Benefits
Modulate CXCR4 receptor activity by interfering with SDF-1 ligand binding.
Inhibit migration of metastatic cancer cells by blocking chemokine receptor signaling.
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Published: 4/23/2024
Contributor(s): Dennis Liotta, James Snyder, Weiqiang Zhan
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