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FIST-15: Interleukin 15, Sushi Domain, and TGF-ß Receptor Fusion Protein Therapeutic
Application
A fusion protein that inhibits TGF-β signaling and enhances activation of CD8+ T cells and natural killer (NK) cells with applications in cancer immunotherapy, treatment of chronic viral infections, and cell therapy.
Key Benefits
Preserves the function of each component, blocking TGF-β signaling while enhancing Interleukin...
Published: 4/23/2024
Contributor(s): Spencer Ng, Jacques Galipeau
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