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Mouse Model for Specific Proteomic Labeling Application Proteomic labeling (labeling of proteins). Key Benefits Method can be used to express TurboID in any cell type. The mouse line can be crossed with any existing Cre line and can be extended to any organ/tissue system. Detection of labeled biomarkers can be identified in biofluids as biomarkers of cell specific disease mechanisms. Can... Published: 12/7/2023       Contributor(s): Srikant Rangaraju, Nicholas Seyfried, Sruti Rayaprolu

Human Brain Proteins with Evidence Consistent with Causality of Alzheimer’s and Depression Application Research and therapeutic targets for Alzheimer’s disease, depression, and other neurological conditions mediated by protein expression in the brain. Key Benefits These findings can be utilized as a research tool to better understand the genetic basis of Alzheimer’s disease. Can also be utilized to develop therapeutics for... Published: 12/20/2023       Contributor(s): Aliza Wingo, Thomas Wingo, Yue Liu, Allan Levey, Nicholas Seyfried, Duc Duong