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CXCR4-Targeting Molecules for Tumor Metastasis and PET Imaging
Application
Positron emission tomography (PET) imaging agents with high specificity for metastatic cancer.
Key Benefits
18F-labeled CXCR4 (partial) antagonist without stem cell mobilizing property is safe to be given to patient multiple times.
Identifies tumor location non-invasively and provides an indication of tumor’s metastatic potential.
Market...
Published: 1/31/2024
Contributor(s): Hyunsuk Shim, Mark Goodman, Dinesh Shetty, Yoon Hyeun Oum
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Precursor PET Compound for Imaging Infections
Application
Diagnostic molecules for detecting bacterial infections using nuclear imaging.
Key Benefits
May improve the detection of infections within the body.
Potentially facilitates earlier treatment and superior clinical outcomes compared to other diagnostic radiotracers.
Market Summary
The rising incidences of bacterial infections resistant...
Published: 4/8/2024
Contributor(s): Mark Goodman, William Robert Taylor, Wone Woo Seo, Malgorzata Lipowska
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Amino Acid-Derived Radiotracer Compounds for PET Cancer Imaging
Application
New class of fluorine-18 labeled amino acid-derived radiotracer compounds for positron emission tomography (PET) cancer imaging.
Key Benefits
Next generation of cancer imaging agents.
Enhanced sensitivity to detect glioblastoma, prostate cancer and other cancers.
Market Summary
PET imaging is a type of nuclear medicine procedure...
Published: 3/19/2024
Contributor(s): Mark Goodman, Lanny Liebeskind, Thomas Pickel
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CRF-1 Receptor Antagonists for PET Imaging or as Potential Therapeutics
ApplicationSmall molecule corticotrophin releasing factor 1 (CRF-1) antagonists, for use as PET imaging agents or potential therapeutics for treating generalized anxiety disorder. Key BenefitsCan image CRF-1 receptor density and distribution via PET Potential antagonist and therapeutics for psychological disorders including anxiety and depression Technical...
Published: 7/28/2023
Contributor(s): Jeffrey Stehouwer, Mark Goodman, Clint Kilts, Charles Nemeroff
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PET Imaging Agents for Tumor Detection
Application Radiolabeled amino acids can be used in conjunction with PET to image tumors or other areas of rapidly proliferating cells. Key BenefitsLabeled amino acids can reliably and readily be produced. Uses non-natural amino acids which are readily transported into cells but not incorporated into new proteins. Increased half-life of the radiolabel...
Published: 11/6/2023
Contributor(s): Mark Goodman
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