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Whole-Animal Genetic Model to Mimic Aspects of the Patient Phenotype of Classic Galactosemia ­ Application An animal model for studying the underlying causes of galactosemia and screening for novel drugs to treat the condition. Key Benefits The first animal model for elucidating the underlying causes of galactosemia in infants. Animals with galactosemia causing genetic knockout exhibit similar disease phenotypes and complications... Published: 7/28/2023       Contributor(s): Judith Fridovich-Keil

Genetically Modified Cell Line With Selectively Impaired O-linked Glycosylation ApplicationGenetically modified cell line which inhibits O-linked glycosylation and produces glycoproteins containing N-linked modifications.Key BenefitsModel system represents epimerase deficiency galactosemia, a variant form of galactosemia.Provides a means to study differing functional mechanisms of N- and O-linked glycosylation.Market SummaryGalactosemia,... Published: 3/1/2024       Contributor(s): Judith Fridovich-Keil, Monty Krieger, Hazel Holden, James Thoden, Jennifer Schulz