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Nox cDNA and Enzymes for Drug Discovery, for Diagnostics, and as Research Tools
Application
Target for drug discovery, gene therapy and to create a diagnostic tool relevant to conditions involving inappropriate cell proliferation.
Technical Summary
Reactive oxygen species (ROS) include superoxide and hydrogen peroxide. ROS are increasingly being recognized as playing a central role in diverse physiologic and pathologic processes....
Published: 4/23/2024
Contributor(s): John David Lambeth, Guang Cheng
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Targeted Drug Development for Abnormal Proliferation
Applications
Target for drug development for diseases involving abnormal proliferation of cells, including psoriasis (hyperproliferation of skin cells) and benign prostatic hypertrophy.
Technical Summary
Reactive oxygen intermediates (ROI) are generated during an oxidative process that occurs in many cell types. The result of generating reactive...
Published: 11/27/2023
Contributor(s): John David Lambeth, Bernard Lassegue, Kathy Griendling, Rebecca Arnold, Guang Cheng
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Mitogenic Oxygenase Regulators for Drug Discovery
Applications
Can be used as a target for drug discovery, gene therapy and, to create a diagnostic tool. These applications are relevant to conditions involving inappropriate cell proliferation (e.g., cancer, atherosclerosis), angiogenesis, and tissue damage associated with inflammatory diseases.
Technical Summary
Reactive oxygen species (ROS) include...
Published: 4/23/2024
Contributor(s): John David Lambeth, Guang Cheng
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